Brain Research, 556 (1991) 344-348 © 1991 Elsevier Science Publishers B.V. All rights reserved. 0006-8993/91/$03.50 ADONIS 0006899391247891

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BRES 24789

von Recklinghausen neurofibroma produces neuronal and glial growth-modulating factors Kiyofumi Asai, Taeko Hotta, Keiko Nakanishi, Jin-ichi Ito, Ryo Tanaka, Takanobu Otsuka, Nobuo Matsui and Taiji Kato Departments of Bioregulation Research, Biochemistry and Orthopedic Surgery, Nagoya Oty University Medical School, Mizuho-Ku, Nagoya 467 (Japan) (Accepted 7 May 1991)

Key words: Neurofibroma, von Recklinghausen; Neurotrophic factor; Glial growth inhibitor; Gliotrophic factor

Two kinds of novel neural trophic factors were currently detected in von Recklinghausen neurofibroma (NF1) extracts. One of the two was a growth factor, neuroblastoma growth factor (Mr50%; - , not significantlydifferent from control (

von Recklinghausen neurofibroma produces neuronal and glial growth-modulating factors.

Two kinds of novel neural trophic factors were currently detected in von Recklinghausen neurofibroma (NF1) extracts. One of the two was a growth facto...
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