ORIGINAL RESEARCH published: 31 October 2015 doi: 10.3389/fnana.2015.00139

Visualization of the medial forebrain bundle using diffusion tensor imaging Ardian Hana 1*, Anisa Hana 2 , Georges Dooms 3 , Hans Boecher-Schwarz 1 and Frank Hertel 1 1

National Service of Neurosurgery, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg, 2 Internal Medicine, Erasmus University of Rotterdam, Rotterdam, Netherlands, 3 Service of Neuroradiology, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg

Edited by: Dave J. Hayes, University of Toronto, Canada Reviewed by: Tifei Yuan, Nanjing Normal University, China Tobias Bracht, Cardiff University Brain Research Imaging Centre, UK *Correspondence: Ardian Hana [email protected] Received: 04 June 2015 Accepted: 15 October 2015 Published: 31 October 2015 Citation: Hana A, Hana A, Dooms G, Boecher-Schwarz H and Hertel F (2015) Visualization of the medial forebrain bundle using diffusion tensor imaging. Front. Neuroanat. 9:139. doi: 10.3389/fnana.2015.00139

Diffusion tensor imaging is a technique that enables physicians the portrayal of white matter tracts in vivo. We used this technique in order to depict the medial forebrain bundle (MFB) in 15 consecutive patients between 2012 and 2015. Men and women of all ages were included. There were six women and nine men. The mean age was 58.6 years (39–77). Nine patients were candidates for an eventual deep brain stimulation. Eight of them suffered from Parkinson‘s disease and one had multiple sclerosis. The remaining six patients suffered from different lesions which were situated in the frontal lobe. These were 2 metastasis, 2 meningiomas, 1 cerebral bleeding, and 1 glioblastoma. We used a 3DT1-sequence for the navigation. Furthermore T2- and DTI- sequences were performed. The FOV was 200 × 200 mm2 , slice thickness 2 mm, and an acquisition matrix of 96 × 96 yielding nearly isotropic voxels of 2 × 2 × 2 mm. 3-Tesla-MRI was carried out strictly axial using 32 gradient directions and one b0-image. We used Echo-Planar-Imaging (EPI) and ASSET parallel imaging with an acceleration factor of 2. b-value was 800 s/mm2 . The maximal angle was 50◦ . Additional scanning time was

Visualization of the medial forebrain bundle using diffusion tensor imaging.

Diffusion tensor imaging is a technique that enables physicians the portrayal of white matter tracts in vivo. We used this technique in order to depic...
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