Downloaded from http://ard.bmj.com/ on October 7, 2017 - Published by group.bmj.com
Clinical and epidemiological research
CONCISE REPORT
Urate crystal deposition in asymptomatic hyperuricaemia and symptomatic gout: a dual energy CT study Nicola Dalbeth,1 Meaghan E House,1 Opetaia Aati,1 Paul Tan,1 Christopher Franklin,1 Anne Horne,1 Gregory D Gamble,1 Lisa K Stamp,2 Anthony J Doyle,3 Fiona M McQueen4 Handling editor Tore K Kvien ▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ annrheumdis-2014-206397). 1
Faculty of Medical and Health Sciences, Department of Medicine, Bone and Joint Research Group, University of Auckland, Auckland, New Zealand 2 Department of Medicine, University of Otago, Christchurch, New Zealand 3 Faculty of Medical and Health Sciences, Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand 4 Faculty of Medical and Health Sciences, Department of Molecular Medicine, University of Auckland, Auckland, New Zealand Correspondence to Dr Nicola Dalbeth, Faculty of Medical and Health Sciences, Department of Medicine, Bone and Joint Research Group, University of Auckland, 85 Park Rd, Grafton, Auckland 1023, New Zealand; [email protected] Received 31 July 2014 Revised 4 December 2014 Accepted 13 January 2015 Published Online First 30 January 2015
To cite: Dalbeth N, House ME, Aati O, et al. Ann Rheum Dis 2015;74:908–911. 908
ABSTRACT Background The aim of this study was to compare the frequency and volume of dual energy CT (DECT) urate deposits in people with asymptomatic hyperuricaemia and symptomatic gout. Methods We analysed DECT scans of the feet from asymptomatic individuals with serum urate ≥540 mmol/L (n=25) and those with crystal proven gout without clinically apparent tophi (n=33). Results DECT urate deposits were observed in 6/25 (24%) participants with asymptomatic hyperuricaemia, 11/14 (79%) with early gout ( predefined as disease duration ≤3 years) and 16/19 (84%) with late gout ( p
Clinical and epidemiological research
CONCISE REPORT
Urate crystal deposition in asymptomatic hyperuricaemia and symptomatic gout: a dual energy CT study Nicola Dalbeth,1 Meaghan E House,1 Opetaia Aati,1 Paul Tan,1 Christopher Franklin,1 Anne Horne,1 Gregory D Gamble,1 Lisa K Stamp,2 Anthony J Doyle,3 Fiona M McQueen4 Handling editor Tore K Kvien ▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ annrheumdis-2014-206397). 1
Faculty of Medical and Health Sciences, Department of Medicine, Bone and Joint Research Group, University of Auckland, Auckland, New Zealand 2 Department of Medicine, University of Otago, Christchurch, New Zealand 3 Faculty of Medical and Health Sciences, Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand 4 Faculty of Medical and Health Sciences, Department of Molecular Medicine, University of Auckland, Auckland, New Zealand Correspondence to Dr Nicola Dalbeth, Faculty of Medical and Health Sciences, Department of Medicine, Bone and Joint Research Group, University of Auckland, 85 Park Rd, Grafton, Auckland 1023, New Zealand; [email protected] Received 31 July 2014 Revised 4 December 2014 Accepted 13 January 2015 Published Online First 30 January 2015
To cite: Dalbeth N, House ME, Aati O, et al. Ann Rheum Dis 2015;74:908–911. 908
ABSTRACT Background The aim of this study was to compare the frequency and volume of dual energy CT (DECT) urate deposits in people with asymptomatic hyperuricaemia and symptomatic gout. Methods We analysed DECT scans of the feet from asymptomatic individuals with serum urate ≥540 mmol/L (n=25) and those with crystal proven gout without clinically apparent tophi (n=33). Results DECT urate deposits were observed in 6/25 (24%) participants with asymptomatic hyperuricaemia, 11/14 (79%) with early gout ( predefined as disease duration ≤3 years) and 16/19 (84%) with late gout ( p
