Nov., 1944]
EDITORIALS
treatment in the first few days of the It cannot be said that hope has been abandoned, but apparently no agent so far available has any specific action of value in the treatment of human typhus. J. L.
instituting disease.
Indian Medical Gazette NOVEMBER
treatment
in the rickettsial DISEASES
adv
tjie recent years with such g development of chemotherapeutic one treatment of many diseases, chem0that so whicli is appointing things has been discovered which therapeutic agent has beentreatment of of undoubted value in the nckettsise. caused by either viruses or geSj y diseases considered to be caused value> hav viruses chemotherapeutic agents may but not because of their action on_ ^ie themselves but because of their appain
.
dusefu^
secondarily infecting organisms.to rently the position with regaid of trachoma, small-pox and p diseases also. So far, the treat?
treatment ~
other
-bl
virus the
diseases with results which sulphonamide group has given would seem to be of little value. gerum of In virus and rickettsial diseases, t but m convalescents has been used opinion this m even regarding the value of
and
rickettsial
is divided.
(see
^prs
,
,
an
Recently however Andrews the stuuy f a Lancet, June 17, .1944) reported series of compounds for ti?n against viruses and j uenzamidine one substance V147 to ^ wjth hydrochloride) which These authois on the rickettsice. type, three strains of rickettsise of the ^ o on the action and results
chemotheiapeutic^
ric^e^
(P-^lP^obraM: appealed ,
.
experimented experimentally infected mice The appeared very promising. have a definite action in development of pulmonary else
an
d
ed t0
g
the
ti
P lesio
following
their
.
in
intranasal inoculation, death in dealtn and number, and also seenwhenthe oms many cases. The effect wasi \ 42 was given before infection, but was de strated if administration ?hus_infected ln ^P, +reatment hours after infection. of treatme or
prevent^
results guinea-pigs, however, the were not
satisfactory. th paper All these results are reported g mentioned above, and they encour PDidemic that these agents might be active,i r,aner is thepaper typhus. Unfortunately however followed by
.
an
addendum briefly 0
trial of the drug in the outbreak Naples. The results were tha disappointing, and it i= stated 1 peutic benefit in cases of typhus
reP?^ed.
be shown
P
EDITORIALS
treatment in the first few days of the It cannot be said that hope has been abandoned, but apparently no agent so far available has any specific action of value in the treatment of human typhus. J. L.
instituting disease.
Indian Medical Gazette NOVEMBER
treatment
in the rickettsial DISEASES
adv
tjie recent years with such g development of chemotherapeutic one treatment of many diseases, chem0that so whicli is appointing things has been discovered which therapeutic agent has beentreatment of of undoubted value in the nckettsise. caused by either viruses or geSj y diseases considered to be caused value> hav viruses chemotherapeutic agents may but not because of their action on_ ^ie themselves but because of their appain
.
dusefu^
secondarily infecting organisms.to rently the position with regaid of trachoma, small-pox and p diseases also. So far, the treat?
treatment ~
other
-bl
virus the
diseases with results which sulphonamide group has given would seem to be of little value. gerum of In virus and rickettsial diseases, t but m convalescents has been used opinion this m even regarding the value of
and
rickettsial
is divided.
(see
^prs
,
,
an
Recently however Andrews the stuuy f a Lancet, June 17, .1944) reported series of compounds for ti?n against viruses and j uenzamidine one substance V147 to ^ wjth hydrochloride) which These authois on the rickettsice. type, three strains of rickettsise of the ^ o on the action and results
chemotheiapeutic^
ric^e^
(P-^lP^obraM: appealed ,
.
experimented experimentally infected mice The appeared very promising. have a definite action in development of pulmonary else
an
d
ed t0
g
the
ti
P lesio
following
their
.
in
intranasal inoculation, death in dealtn and number, and also seenwhenthe oms many cases. The effect wasi \ 42 was given before infection, but was de strated if administration ?hus_infected ln ^P, +reatment hours after infection. of treatme or
prevent^
results guinea-pigs, however, the were not
satisfactory. th paper All these results are reported g mentioned above, and they encour PDidemic that these agents might be active,i r,aner is thepaper typhus. Unfortunately however followed by
.
an
addendum briefly 0
trial of the drug in the outbreak Naples. The results were tha disappointing, and it i= stated 1 peutic benefit in cases of typhus
reP?^ed.
be shown
P
