Towards evidence-based computational statistics: lessons from clinical research on the role and design of real-data benchmark studies.

The goal of medical research is to develop interventions that are in some sense superior, with respect to patient outcome, to interventions currently ...
522KB Sizes 2 Downloads 8 Views

Recommend Documents


Using the Clinical Research Network for psychosocial cancer research: lessons learned from two observational studies.
Patient recruitment to psychosocial oncology research has increased but the many studies have been single-site or small-scale. The National Institute for Health Research Clinical Research Network, supports National Institute for Health Research portf

Endothelin receptor antagonists in clinical research--lessons learned from preclinical and clinical kidney studies.
Endothelin receptor antagonists (ETRAs) are approved for the treatment of pulmonary hypertension and scleroderma-related digital ulcers. The efforts to approve this class of drugs for renal indications, however, failed so far. Preclinical studies wer

Towards the computational design of protein post-translational regulation.
Protein post-translational modifications (PTMs) are a fast and versatility mechanism used by the cell to regulate the function of proteins in response to changing conditions. PTMs can alter the activity of proteins by allosteric regulation or by cont

Strategies for mHealth research: lessons from 3 mobile intervention studies.
The capacity of Mobile Health (mHealth) technologies to propel healthcare forward is directly linked to the quality of mobile interventions developed through careful mHealth research. mHealth research entails several unique characteristics, including

Advances and computational tools towards predictable design in biological engineering.
The design process of complex systems in all the fields of engineering requires a set of quantitatively characterized components and a method to predict the output of systems composed by such elements. This strategy relies on the modularity of the us

Statistics in clinical research: Important considerations.
Statistical analysis is one of the foundations of evidence-based clinical practice, a key in conducting new clinical research and in evaluating and applying prior research. In this paper, we review the choice of statistical procedures, analyses of th

[Lessons from Field Studies].
During my academic career for more than 40 years, I was involved in 18 epidemiological field studies, partially or fully. Among these field studies, four (1. Medical services in remote rural areas in Okinawa, 2. Yusho episode, 3. JICA Onchocerciasis