HHS Public Access Author manuscript Author Manuscript
HIV Med. Author manuscript; available in PMC 2017 September 01. Published in final edited form as: HIV Med. 2016 September ; 17(8): 601–604. doi:10.1111/hiv.12360.
Administering Influenza Vaccine to HIV Patients: Does Timing Matter? Elizabeth R. GLINKA, Pharm.D., BCPS, Pharmacy, San Diego Veterans Affairs Healthcare System; San Diego, California, USA
Author Manuscript
Davey M. SMITH, MD, and Infectious Diseases, San Diego Veterans Affairs Healthcare Administration; San Diego, California, USA. University of California San Diego; La Jolla, California, USA Scott T. JOHNS, Pharm.D., BCPS (ID) San Diego Veterans Affairs Healthcare System; San Diego, California, USA
Abstract Objectives—Patients with human immunodeficiency virus (HIV) vaccinated early in the flu season are more likely to get influenza or influenza like illness (ILL) compared to late vaccination. Design—It is known that antibody titers wane over time, particularly among individuals with HIV infection. It is unclear if the timing of influenza vaccination within the flu season affects the probability of an influenza infection later during flu season.
Author Manuscript
Methods—A retrospective cohort study of HIV patients in care at Department of Veteran’s Affairs San Diego Healthcare System was conducted from 9/1/2005 – 5/31/2013. Among these patients, we evaluated if there was a relationship between the timing of influenza vaccination and incidence of laboratory confirmed influenza, influenza diagnosed by a physician, or influenza like illness (ILI). Results—Patients who received influenza vaccine early in the season were more likely to contract influenza or ILI than patients who were vaccinated late (p
HIV Med. Author manuscript; available in PMC 2017 September 01. Published in final edited form as: HIV Med. 2016 September ; 17(8): 601–604. doi:10.1111/hiv.12360.
Administering Influenza Vaccine to HIV Patients: Does Timing Matter? Elizabeth R. GLINKA, Pharm.D., BCPS, Pharmacy, San Diego Veterans Affairs Healthcare System; San Diego, California, USA
Author Manuscript
Davey M. SMITH, MD, and Infectious Diseases, San Diego Veterans Affairs Healthcare Administration; San Diego, California, USA. University of California San Diego; La Jolla, California, USA Scott T. JOHNS, Pharm.D., BCPS (ID) San Diego Veterans Affairs Healthcare System; San Diego, California, USA
Abstract Objectives—Patients with human immunodeficiency virus (HIV) vaccinated early in the flu season are more likely to get influenza or influenza like illness (ILL) compared to late vaccination. Design—It is known that antibody titers wane over time, particularly among individuals with HIV infection. It is unclear if the timing of influenza vaccination within the flu season affects the probability of an influenza infection later during flu season.
Author Manuscript
Methods—A retrospective cohort study of HIV patients in care at Department of Veteran’s Affairs San Diego Healthcare System was conducted from 9/1/2005 – 5/31/2013. Among these patients, we evaluated if there was a relationship between the timing of influenza vaccination and incidence of laboratory confirmed influenza, influenza diagnosed by a physician, or influenza like illness (ILI). Results—Patients who received influenza vaccine early in the season were more likely to contract influenza or ILI than patients who were vaccinated late (p
