The Role of High Density Lipoprotein Apolipoprotein CII in Triglyceride Metabolism M.L. KASHYAP, L.S. SRIVASTAVA, B.A. HYND, G. PERISUTTI, D.W. BRADY, P. GARTSIDE, and C.J. GLUECK, Lipid Research Clinic, Division of Metabolism, and General Clinical Research Center, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 ABSTRACT
The purpose of these studies was (a) to examine the relationship between total plasma triglycerides (TG) and the amount of apolipoprotein CII (apo CII) in triglyceride rich lipoproteins (TRL), and (b) to determine whether TRL could be enriched with apo CII in vitro. In 13 patients with primary endogenous hypertriglyceridemia, (logl0) total plasma TG correlated inversely with the amount of apo CII per unit very low density lipoprotein (VLDL) protein (r = -0,76; p
The purpose of these studies was (a) to examine the relationship between total plasma triglycerides (TG) and the amount of apolipoprotein CII (apo CII) in triglyceride rich lipoproteins (TRL), and (b) to determine whether TRL could be enriched with apo CII in vitro. In 13 patients with primary endogenous hypertriglyceridemia, (logl0) total plasma TG correlated inversely with the amount of apo CII per unit very low density lipoprotein (VLDL) protein (r = -0,76; p
