186 Zhu et al

World J Emerg Med, Vol 3, No 3, 2012

Original Article

The relationship between serum levels of uric acid and prognosis of infection in critically ill patients He-chen Zhu, Ruo-lan Cao ICU, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China Corresponding Author: He-chen Zhu, Email: [email protected]

BACKGROUND: Serum uric acid level is associated with some chronic diseases and prognosis of severe infection. This study aimed to investigate the relationship between serum uric acid (SUA) and prognosis of infection in critically ill patients. METHODS: The data from 471 patients with infection admitted from January 2003 to April 2010 were analyzed retrospectively at Huashan Hospital Affiliated to Fudan University, Shanghai, China. The data of SUA, serum creatinine, blood urea nitrogen (BUN) and other relevant examinations within 24 hours after admission were recorded and the levels of SUA in those patients were described, then Student's t test was used to evaluate the relationship between SUA and pre-existing disorders. Different levels of SUA were graded for further analysis. The Chi-square test was used to examine the difference in the prognosis of infection. RESULTS: The mean initial level of SUA within 24 hours after admission was 0.232±0.131 mmol/L and the median was 0.199 mmol/L. Remarkable variations in the initial levels of SUA were observed in patients with pre-existing hypertension (t=–3.084, P=0.002), diabetes mellitus (t=–2.487, P=0.013), cerebral infarction (t=–3.061, P=0.002), renal insufficiency (t=–4.547, P

The relationship between serum levels of uric acid and prognosis of infection in critically ill patients.

Serum uric acid level is associated with some chronic diseases and prognosis of severe infection. This study aimed to investigate the relationship bet...
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