GYNECOLOGIC

ONCOLOGY

46,74-81(1992)

The Psychological, Social, and Sexual Consequences of Gestational Trophoblastic Disease LARI WENZEL,

PH.D.,*

Ross BERKOWITZ,

M.D.,?,’ DONALD

SHARON ROBINSON, PH.D.,$ MARILYN GOLDSTEIN, M.D.?

BERNSTEIN,

M.H.P.,?

AND

*Memorial Cancer Institute, Long Beach Memorial Medical Center, Long Beach, California 90801; and Department of Obstetrics and Gynecology, University of California at Irvine, Irvine, California 92717; tDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, New England Trophoblastic Disease Center, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 0211s; and *Department of Counseling Psychology, Arizona State University, Tempe, Arizona 85287

Received October 7. 1991

Seventy-six women diagnosedwith gestational trophoblastic disease(GTD) from 1985to 1989completedquestionnairesevaluating their status on mood disturbance, marital satisfaction, sexual functioning, psychosocialresponseto illness, and report of the most stressfulevent occurring within the past year. Multivariate analysesof variance (MANOVA) were conducted on dependentmeasuresto examine differencesbetweendiagnostic groups (partial mole, complete mole, persistentdisease),time from diagnosis(