Accepted Manuscript The Maccabi Glaucoma Study- Prevalence and Incidence of Glaucoma in a Large Israeli Health Maintenance Organization Hani Levkovitch-Verbin, MD,MPA Inbal Goldshtein, Msc Gabriel Chodick, PhD Nir Zigman, BA Varda Shalev, MD PII:
S0002-9394(14)00229-3
DOI:
10.1016/j.ajo.2014.04.026
Reference:
AJOPHT 8903
To appear in:
American Journal of Ophthalmology
Received Date: 24 December 2013 Revised Date:
28 April 2014
Accepted Date: 28 April 2014
Please cite this article as: Levkovitch-Verbin H, Goldshtein I, Chodick G, Zigman N, Shalev V, The Maccabi Glaucoma Study- Prevalence and Incidence of Glaucoma in a Large Israeli Health Maintenance Organization, American Journal of Ophthalmology (2014), doi: 10.1016/j.ajo.2014.04.026. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT THE MACCABI GLAUCOMA STUDY- PREVALENCE AND INCIDENCE OF GLAUCOMA IN A LARGE ISRAELI HEALTH MAINTENANCE ORGANIZATION
Hani Levkovitch-Verbin MD,MPA1,2,3,Inbal Goldshtein Msc 1, Gabriel Chodick PhD 1,2 , Nir Zigman BA1, Varda Shalev MD1,2 Medical division, Maccabi Healthcare Services, Tel Aviv, Israel
RI PT
1 2
SacklerFaculty of Medicine, Tel Aviv University, Tel Aviv, Israel
3
Goldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel
SC
Running head/ short title:
Glaucoma epidemiology in a large healthcare organization
M AN U
Correspondence:
Hani Levkovitch-Verbin, Maccabi Healthcare Services, 27 Ha'Mered Street Tel Aviv 68125 Israel. Tel: 972 3 5344608 Fax: 972 3 7952680 E-mail: [email protected], [email protected]
AC C
EP
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Word count: 2,211
0
ACCEPTED MANUSCRIPT ABSTRACT PURPOSE: To investigate the prevalence and incidence of glaucoma in a large health maintenance organization (HMO) in Israel. DESIGN: A population-based retrospective cohort study, conducted using electronic medical database.
RI PT
METHODS: Collected data included personal and medical characteristics. Settings: Maccabi Healthcare Services, the second largest HMO in Israel insuring 2 million members and serving 25% of the population with a nationwide distribution.
SC
Study population: Maccabi members from January 2003 to December 2010.
M AN U
Main Outcome Measures: Prevalence and incidence of glaucoma according to the International Classification of Diseases, 9th revision, Clinical Modification diagnostic codes.
EP
TE D
RESULTS: A total of 15,708 prevalent glaucoma patients were identified among active members of Maccabi in December 2010. A total of 15,332(97.6%) were 40 years or older, with a point prevalence of 2.2%. Prevalence of glaucoma was strongly associated with age, ranging from 0.28%at age 40-50 to 9.2% among elderly aged 80 or above. The 5 most prevalent diagnoses were open angle glaucoma (1.61%), exfoliation glaucoma (0.20%), unspecified glaucoma (0.17%), angle closure (0.11%), and normal tension glaucoma (0.06%). We identified 6,674 incident glaucoma patients diagnosed between 2003 and 2010. The observed incidence density rate among 40+ year old members was 1.84 (1.79-1.88) new cases per 1000 person years. Median age at diagnosis was 64 years old. The risk of glaucoma was similar between sexes up to age 70 years, and was significantly (P
S0002-9394(14)00229-3
DOI:
10.1016/j.ajo.2014.04.026
Reference:
AJOPHT 8903
To appear in:
American Journal of Ophthalmology
Received Date: 24 December 2013 Revised Date:
28 April 2014
Accepted Date: 28 April 2014
Please cite this article as: Levkovitch-Verbin H, Goldshtein I, Chodick G, Zigman N, Shalev V, The Maccabi Glaucoma Study- Prevalence and Incidence of Glaucoma in a Large Israeli Health Maintenance Organization, American Journal of Ophthalmology (2014), doi: 10.1016/j.ajo.2014.04.026. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT THE MACCABI GLAUCOMA STUDY- PREVALENCE AND INCIDENCE OF GLAUCOMA IN A LARGE ISRAELI HEALTH MAINTENANCE ORGANIZATION
Hani Levkovitch-Verbin MD,MPA1,2,3,Inbal Goldshtein Msc 1, Gabriel Chodick PhD 1,2 , Nir Zigman BA1, Varda Shalev MD1,2 Medical division, Maccabi Healthcare Services, Tel Aviv, Israel
RI PT
1 2
SacklerFaculty of Medicine, Tel Aviv University, Tel Aviv, Israel
3
Goldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel
SC
Running head/ short title:
Glaucoma epidemiology in a large healthcare organization
M AN U
Correspondence:
Hani Levkovitch-Verbin, Maccabi Healthcare Services, 27 Ha'Mered Street Tel Aviv 68125 Israel. Tel: 972 3 5344608 Fax: 972 3 7952680 E-mail: [email protected], [email protected]
AC C
EP
TE D
Word count: 2,211
0
ACCEPTED MANUSCRIPT ABSTRACT PURPOSE: To investigate the prevalence and incidence of glaucoma in a large health maintenance organization (HMO) in Israel. DESIGN: A population-based retrospective cohort study, conducted using electronic medical database.
RI PT
METHODS: Collected data included personal and medical characteristics. Settings: Maccabi Healthcare Services, the second largest HMO in Israel insuring 2 million members and serving 25% of the population with a nationwide distribution.
SC
Study population: Maccabi members from January 2003 to December 2010.
M AN U
Main Outcome Measures: Prevalence and incidence of glaucoma according to the International Classification of Diseases, 9th revision, Clinical Modification diagnostic codes.
EP
TE D
RESULTS: A total of 15,708 prevalent glaucoma patients were identified among active members of Maccabi in December 2010. A total of 15,332(97.6%) were 40 years or older, with a point prevalence of 2.2%. Prevalence of glaucoma was strongly associated with age, ranging from 0.28%at age 40-50 to 9.2% among elderly aged 80 or above. The 5 most prevalent diagnoses were open angle glaucoma (1.61%), exfoliation glaucoma (0.20%), unspecified glaucoma (0.17%), angle closure (0.11%), and normal tension glaucoma (0.06%). We identified 6,674 incident glaucoma patients diagnosed between 2003 and 2010. The observed incidence density rate among 40+ year old members was 1.84 (1.79-1.88) new cases per 1000 person years. Median age at diagnosis was 64 years old. The risk of glaucoma was similar between sexes up to age 70 years, and was significantly (P
