Eur J Clin Microbiol Infect Dis DOI 10.1007/s10096-013-2033-3
ARTICLE
The incidence and clinical symptomatology of Clostridium difficile infections in a community setting in a cohort of Danish patients attending general practice L. M. Søes & H. M. Holt & B. Böttiger & H. V. Nielsen & M. Torpdahl & E. M. Nielsen & S. Ethelberg & K. Mølbak & V. Andreasen & M. Kemp & K. E. P. Olsen
Received: 3 October 2013 / Accepted: 5 December 2013 # Springer-Verlag Berlin Heidelberg 2013
Abstract Clostridium difficile infection (CDI) is gradually being recognised as a cause of morbidity in the community. We investigated the incidence and clinical characteristics of CDI in a community setting and characterised the C. difficile strains by toxin gene profiling and polymerase chain reaction (PCR) ribotyping. Patients included in the study had attended general practice, primarily because of diarrhoea; CDI patients (259 patients; 121 38 °C, weight loss and sick leave. Data were analysed by logistic regression. CDI patients 15 days (59 % vs. 73 %) as the predominant symptoms. CDI patients ≥2 years old reported duration of diarrhoea >15 days more often compared to non-CDI patients (73 % vs. 27 %, p 10 per day in 38 % of patients with toxin- and culture-positive CDI [7]. A recent study found that patients with community-acquired CDI were less likely to have comorbidities and severe
Eur J Clin Microbiol Infect Dis
infection compared to patients with hospital-acquired infection [3]. The existence of CDI in early childhood is debated, and, on this basis, most studies exclude children
ARTICLE
The incidence and clinical symptomatology of Clostridium difficile infections in a community setting in a cohort of Danish patients attending general practice L. M. Søes & H. M. Holt & B. Böttiger & H. V. Nielsen & M. Torpdahl & E. M. Nielsen & S. Ethelberg & K. Mølbak & V. Andreasen & M. Kemp & K. E. P. Olsen
Received: 3 October 2013 / Accepted: 5 December 2013 # Springer-Verlag Berlin Heidelberg 2013
Abstract Clostridium difficile infection (CDI) is gradually being recognised as a cause of morbidity in the community. We investigated the incidence and clinical characteristics of CDI in a community setting and characterised the C. difficile strains by toxin gene profiling and polymerase chain reaction (PCR) ribotyping. Patients included in the study had attended general practice, primarily because of diarrhoea; CDI patients (259 patients; 121 38 °C, weight loss and sick leave. Data were analysed by logistic regression. CDI patients 15 days (59 % vs. 73 %) as the predominant symptoms. CDI patients ≥2 years old reported duration of diarrhoea >15 days more often compared to non-CDI patients (73 % vs. 27 %, p 10 per day in 38 % of patients with toxin- and culture-positive CDI [7]. A recent study found that patients with community-acquired CDI were less likely to have comorbidities and severe
Eur J Clin Microbiol Infect Dis
infection compared to patients with hospital-acquired infection [3]. The existence of CDI in early childhood is debated, and, on this basis, most studies exclude children
