Exp Brain Res (1992) 90 : 271-274

Experimental BrainResearch 9 Springer-Verlag1992

The area postrema is not involved in osmotic activation of neurosecretory cells in the supraoptic nucleus K. Honda, T. Higuchi, S. Takano, and H. Negoro Department of Physiology, Fukui Medical School, Matsuoka, Fukui 910-11, Japan Received August 12, 1991 / Accepted March 9, 1992

Summary. Experiments were performed to examine whether or not the area postrema (AP) is involved in the osmotic control of neurohypophysial hormone release. In control rats and in rats bearing extensive lesions of AP, extracellular action potentials were recorded from neurosecretory cells in the supraoptic nucleus (SON) and firing rates determined before and after the intraperitoheal (i.p.) injection of 1.5 M-NaC1 solution. Lesion of the AP significantly (p

The area postrema is not involved in osmotic activation of neurosecretory cells in the supraoptic nucleus.

Experiments were performed to examine whether or not the area postrema (AP) is involved in the osmotic control of neurohypophysial hormone release. In...
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