Accepted Manuscript Surgical treatment of sebaceous cyst in spine region Li-Feng Lao, MD, PhD Gui-Bin Zhong, MD, PhD Zu-De Liu, MD, PhD PII:
S1529-9430(14)00383-0
DOI:
10.1016/j.spinee.2014.04.007
Reference:
SPINEE 55858
To appear in:
The Spine Journal
Received Date: 18 February 2014 Revised Date:
17 March 2014
Accepted Date: 9 April 2014
Please cite this article as: Lao L-F, Zhong G-B, Liu Z-D, Surgical treatment of sebaceous cyst in spine region, The Spine Journal (2014), doi: 10.1016/j.spinee.2014.04.007. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Surgical treatment of sebaceous cyst in spine region
RI PT
Li-Feng Lao, MD, PhD, Gui-Bin Zhong, MD, PhD, Zu-De Liu, MD, PhD
Department of Orthopaedic Surgery, Renji Hospital, Shanghai Jiaotong University School of
Dr. Gui-Bin Zhong, MD, PhD
TE D
Professor of Orthopaedic Surgery
M AN U
Corresponding Author:
SC
Medicine, Shanghai 200127, China
Renji Hospital, Shanghai Jiaotong University School of Medicine 1630 Dongfang Road, Shanghai, 200127, China
EP
Phone: 86-21-68383725, Fax: 86-21-58394262
AC C
E-mail: [email protected]
ACCEPTED MANUSCRIPT
Surgical treatment of sebaceous cyst in spine region
2
In 2003 a 42 year old otherwise healthy woman presented with low back pain to an outside
3
hospital. Radiographs revealed vertebral destruction (Fig. 1A, 1B). An MRI showed a mass with
4
intermediate signal intensity on T1 images and high signal intensity on T2 images, consistent with
5
tumor, tuberculosis, or abscess (Fig. 1C, 1D). Antituberculous therapy was prescribed, to no effect.
6
Debridement with internal fixation was performed. Pathology was reported to be consistent with a
7
sebaceous cyst. She had a second surgery in 2007 for additional debridement and removal of the
8
internal fixation, which had loosened. She presented to our institution in 2010 with worsened bony
9
destruction (Fig. 1E, 1F, Fig. 2A, 2B). Additional debridement with T10-S1 internal fixation was
M AN U
SC
RI PT
1
performed (Fig. 2C, 2D). The postoperative pathology was sebaceous cyst (Fig. 3).
11
References
12
[1] Becker GW, Battersby RD. Spinal neurenteric cyst presenting as recurrent midline sebaceous
13
cysts. Ann R Coll Surg Engl 2005;87:W1-4.
14
[2] Munshi A, Talapatra K, Ramadwar M, et al. Spinal epidermoid cyst with sudden onset of
15
paraplegia. J Cancer Res Ther 2009;5:290-2.
16
[3] Gonzalvo A, Hall N, McMahon JH, et al. Intramedullary spinal epidermoid cyst of the upper
17
thoracic region. J Clin Neurosci 2009;16:142-4.
18
Figure legend
19
Fig. 1. (A, B) Posteroanterior and lateral X-rays of lumbar spine in 2005 showing vertebral
20
destruction. (C, D) Sagittal plane of lumbar MRI scan in 2005. (E, F) Posteroanterior and lateral
21
X-rays of lumbar in 2010 before the third surgery. Fig. 2 (A, B) Coronal and sagittal
22
reconstruction of CT scans showed mass in spine region before the third surgery. (C, D)
AC C
EP
TE D
10
1
ACCEPTED MANUSCRIPT Posteroanterior and lateral X-rays of lumbar spine in 2010 postoperatively. Fig. 3. Pathologic
2
histology with magnification 4 *10 and with magnification 10 *10 (A-D). The cyst was filled with
3
sebaceous gland cells and cholesterol crystal. The outer layer of capsule wall was fibrous
4
connective tissue and inner layer was epithelial cells, containing sebaceous gland structure.
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AC C
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ACCEPTED MANUSCRIPT
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TE D
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ACCEPTED MANUSCRIPT
AC C
EP
TE D
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SC
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ACCEPTED MANUSCRIPT
S1529-9430(14)00383-0
DOI:
10.1016/j.spinee.2014.04.007
Reference:
SPINEE 55858
To appear in:
The Spine Journal
Received Date: 18 February 2014 Revised Date:
17 March 2014
Accepted Date: 9 April 2014
Please cite this article as: Lao L-F, Zhong G-B, Liu Z-D, Surgical treatment of sebaceous cyst in spine region, The Spine Journal (2014), doi: 10.1016/j.spinee.2014.04.007. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Surgical treatment of sebaceous cyst in spine region
RI PT
Li-Feng Lao, MD, PhD, Gui-Bin Zhong, MD, PhD, Zu-De Liu, MD, PhD
Department of Orthopaedic Surgery, Renji Hospital, Shanghai Jiaotong University School of
Dr. Gui-Bin Zhong, MD, PhD
TE D
Professor of Orthopaedic Surgery
M AN U
Corresponding Author:
SC
Medicine, Shanghai 200127, China
Renji Hospital, Shanghai Jiaotong University School of Medicine 1630 Dongfang Road, Shanghai, 200127, China
EP
Phone: 86-21-68383725, Fax: 86-21-58394262
AC C
E-mail: [email protected]
ACCEPTED MANUSCRIPT
Surgical treatment of sebaceous cyst in spine region
2
In 2003 a 42 year old otherwise healthy woman presented with low back pain to an outside
3
hospital. Radiographs revealed vertebral destruction (Fig. 1A, 1B). An MRI showed a mass with
4
intermediate signal intensity on T1 images and high signal intensity on T2 images, consistent with
5
tumor, tuberculosis, or abscess (Fig. 1C, 1D). Antituberculous therapy was prescribed, to no effect.
6
Debridement with internal fixation was performed. Pathology was reported to be consistent with a
7
sebaceous cyst. She had a second surgery in 2007 for additional debridement and removal of the
8
internal fixation, which had loosened. She presented to our institution in 2010 with worsened bony
9
destruction (Fig. 1E, 1F, Fig. 2A, 2B). Additional debridement with T10-S1 internal fixation was
M AN U
SC
RI PT
1
performed (Fig. 2C, 2D). The postoperative pathology was sebaceous cyst (Fig. 3).
11
References
12
[1] Becker GW, Battersby RD. Spinal neurenteric cyst presenting as recurrent midline sebaceous
13
cysts. Ann R Coll Surg Engl 2005;87:W1-4.
14
[2] Munshi A, Talapatra K, Ramadwar M, et al. Spinal epidermoid cyst with sudden onset of
15
paraplegia. J Cancer Res Ther 2009;5:290-2.
16
[3] Gonzalvo A, Hall N, McMahon JH, et al. Intramedullary spinal epidermoid cyst of the upper
17
thoracic region. J Clin Neurosci 2009;16:142-4.
18
Figure legend
19
Fig. 1. (A, B) Posteroanterior and lateral X-rays of lumbar spine in 2005 showing vertebral
20
destruction. (C, D) Sagittal plane of lumbar MRI scan in 2005. (E, F) Posteroanterior and lateral
21
X-rays of lumbar in 2010 before the third surgery. Fig. 2 (A, B) Coronal and sagittal
22
reconstruction of CT scans showed mass in spine region before the third surgery. (C, D)
AC C
EP
TE D
10
1
ACCEPTED MANUSCRIPT Posteroanterior and lateral X-rays of lumbar spine in 2010 postoperatively. Fig. 3. Pathologic
2
histology with magnification 4 *10 and with magnification 10 *10 (A-D). The cyst was filled with
3
sebaceous gland cells and cholesterol crystal. The outer layer of capsule wall was fibrous
4
connective tissue and inner layer was epithelial cells, containing sebaceous gland structure.
AC C
EP
TE D
M AN U
SC
RI PT
1
2
AC C
EP
TE D
M AN U
SC
RI PT
ACCEPTED MANUSCRIPT
AC C
EP
TE D
M AN U
SC
RI PT
ACCEPTED MANUSCRIPT
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ACCEPTED MANUSCRIPT
