JouRNAL OF VIROLOGY, Nov. 1977, p. 709-711 Copyright i 1977 American Society for Microbiology
Vol. 24, No.2 Printed in U.S.A.
Superinfection Exclusion by Bacteriophage T7 WILLIAM T. McALLISTER AND CORNELIA L. BARRETT Department of Microbiology, CoUege of Medicine and Dentistry of New Jersey, Rutgers Medical School,
Piscataway, New Jersey 08854
Received for publication 2 June 1977
Only two of the early genes of bacteriophage T7 were found to play a significant role in exclusion of superinfecting bacteriophage T3 particles; genes 0.3 and 1. Protein synthesis by the preinfecting phage particle was not required for efficient exclusion. These findings are discussed with regard to the known functions of these genes during T7 development. Bacteriophages T3 and T7, although closely related, are observed to exclude one another during mixed infection (9, 10). If a cell is infected simultaneously with both viruses, only one or the other viral type is found among the progeny; only rarely (
Vol. 24, No.2 Printed in U.S.A.
Superinfection Exclusion by Bacteriophage T7 WILLIAM T. McALLISTER AND CORNELIA L. BARRETT Department of Microbiology, CoUege of Medicine and Dentistry of New Jersey, Rutgers Medical School,
Piscataway, New Jersey 08854
Received for publication 2 June 1977
Only two of the early genes of bacteriophage T7 were found to play a significant role in exclusion of superinfecting bacteriophage T3 particles; genes 0.3 and 1. Protein synthesis by the preinfecting phage particle was not required for efficient exclusion. These findings are discussed with regard to the known functions of these genes during T7 development. Bacteriophages T3 and T7, although closely related, are observed to exclude one another during mixed infection (9, 10). If a cell is infected simultaneously with both viruses, only one or the other viral type is found among the progeny; only rarely (
