Eur Radiol (2014) 24:3217–3223 DOI 10.1007/s00330-014-3340-5

MUSCULOSKELETAL

Study of proximal femoral bone perfusion with 3D T1 dynamic contrast-enhanced MRI: a feasibility study Jean-François Budzik & Guillaume Lefebvre & Gerard Forzy & Mazen El Rafei & David Chechin & Anne Cotten

Received: 19 December 2013 / Revised: 28 May 2014 / Accepted: 10 July 2014 / Published online: 14 August 2014 # European Society of Radiology 2014

Abstract Objective The objective of this study was to compare measurements of semi-quantitative and pharmacokinetic parameters in areas of red (RBM) and yellow bone marrow (YBM) of the hip, using an in-house high-resolution DCE T1 sequence, and to assess intra- and inter-observer reproducibility of these measurements. Methods The right hips of 21 adult patients under 50 years of age were studied. Spatial resolution was 1.8×1.8×1.8 mm3, and temporal resolution was 13.5 seconds. Two musculoskeletal radiologists independently processed DCE images and measured semi-quantitative and pharmacokinetic parameters in areas of YBM and RBM. Signal-to-noise (SNR) and contrast-to-noise (CNR) ratios were calculated. Intra- and inter-observer reproducibility was assessed. Results Area under the curve (AUC) and initial slope (IS) were significantly greater for RBM than for YBM (p

Study of proximal femoral bone perfusion with 3D T1 dynamic contrast-enhanced MRI: a feasibility study.

The objective of this study was to compare measurements of semi-quantitative and pharmacokinetic parameters in areas of red (RBM) and yellow bone marr...
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