Kidney International, Vol. 12 (1977), pp. 412—421

Sodium, renin, aldosterone, catecholamines, and blood pressure in diabetes mellitus RUDOLF DE CHATEL, PETER WEIDMANN, JOSEF FLAMMER, WALTER H. ZIEGLER, CARLO

BERETTA-PICCOLI, WILHELM VETTER and F1NçoIs C. REUBI Departments of Medicine, Universities of Berne and Zurich, Switzerland

Sodium, renin, aldosterone, catecholamines, and blood pressure in diabetes mellitus. Interrelations among plasma renin activity (PRA), aldosterone and cortisol levels, blood volume, exchangeable sodium, urinary catecholamines, and blood pressure were studied in 35 normal subjects and 60 age-matched non-azotemic patients with diabetes mellitus (60% with hypertension, 15% with orthostatic hypotension). Basal PRA, plasma aldosterone, cortisol, blood volume, plasma potassium, and urinary electrolytes

tions de Ia pression artérielle liées a l'orthostatisme sont correlées (P < 0,01) a Ia fois avec l'excrétion de catécholamines et Ia PRA de base. Ceci suggère qu'au cours du diabète le sodium corporel

patients, however, had a 10% increase in body sodium (P