This

lie

the

terras

snake-bite

urgency treatment of The curative treatment

poisoning.

requires? Free incisions into all the

4.

inflamed

and the

tissues,

into these tissues of

15 per cent, solution of

a

of

potassium. Multiple injections of

permanganate 5.

into all the inflamed the

region

6.

The

the

but

regions,

of all the inof

by permanganate from half

potassium

inch to

an

an

the needle to be driven into the

tissues

just beyond the point being carried into

line of

border of the indurated

area.

The involved

permanganate

inch

healthy

demarcation, its deepest part of the

the

should be dressed

area

of lint saturated

means

in

particularly

complete surrounding

injections placed

7.

solution

same

of the wound.

volved tissues

apart,

of the

portions

thorough kneading

by

15 per cent, of

with

potassium solution.

of

Dr. Barber recommends that the permanganate of potassium should be used freely without and he has used

stint,

much

as

half drachms of the pure would not hesitate to use

one

as

and

drug diluted, four

times

a

and that

if necessary, as it seems to exert no deleterious effect either locally or generally. Stimulants should be given according to the

quantity

condition of the

diaphoretics

Laxatives, diuretics, and

pulse.

should also be administered to aid

in the elimination of the He records

poison.

and has had in all nine, single death. He began the

four,

without a treatment 24 hours after the patient was struck in the first case, 20 hours in the second case, cases

and 14 hours in the third case; and it is evident from this that the poison of the rattlesnake is

much slower in its action than that of the cobra, and gives more time for the application

SNAKE-BITES. Dr.

Barber,

of

a

rattlesnake

Wyoming, formupoisoning by the bite

Governor of

lates the treatment for as

Richards

remedy, pointed

made

was ?

and immediate cauterization; or, if this is not practicable, sucking the wound. 2. The immediate application of an intermittent for may

tourniquet,?that is, a

moment at

a

gain admission

one

time,?so

which is relaxed that the

poison

to the circulation in small

3.

The free administration of alcohol

bonate of

ammonium.

or car-

than

more

was

application 20

Vincent

Dr.

late

of little avail

of the

minutes

was

ly

.)

advocated in Australia.

Mueller,

lays

It

was

strong-

introduced

by

and received

the Editor of the who

the

bitten.

Another method of treatment has been

Dr.

remedy

after

?

patient

ment

doses.

the

for

out that it

in cobra bite if the

follows:?

Free incision to the bottom of the wound

1.

of this

strong support from Australian Medical Gazette,

down the

following principles

of treat-

:?

Endeavours should be made to eliminate the venom

previous

to its

absorption

at the incision

Oct. or

be

Neither alcohol nor ammonia should either by the mouth or beneath the

bite.

given,

skin,

by

of toxic

should not be

patient's strength

and the

exhausted ance

SNAKE-BITES.

1894.]

violent exercise. On the appearsymptoms the treatment by hypo-

dermic injections of strychnine should be begun. At least one-tenth of a grain should be in-

jected

skin,

under the

sixth if the

or even a

insensibility is very marked. be repeated in 20 minutes

successfully

The number of manner

the

coma

in which he

cases

has led other

satisfactory. three injections at another

patient,

One

woman

recovered with

intervals of 15 minutes,,? who had been taken seventy

of the arm by an Esmarch bandage; to effectual local depletion; and to the employment of

strychnia.

These were all cases of tiger-snake bite. But Hunt of Queensland reported the case of a child, aged sixteen months, who had been bitten by a death adder. Three hours previous to the treatment, immediately after the bite, the finger of

the child was cut off and the stump sucked by its relatives, who also drenched it with ammonia and applied ligatures to the arm. The child when seen was almost comatose ; the pupils were dilated and insensible to light; the pulse feeble and irregular, and the face pinched and cyanotic. One thirtieth of a grain of strychnia was injected into the arm, the ligatures removed a

Faradic current

neck and after the

spine.

applied

A second

to the nape of the

dose,

15 minutes and then the child

injected, began to improve; slight twitches occurred, the child made a perfect recovery. first,

was

boy was a symptoms

little

drowsy,

but he had

spasm and vomited.

a steamer for medical aid, and was almost comatose, recovered with a single injection. In a third case reported by Dr. Stoker, recovery was attributed by him to effective ligaturing

and

marked

practi-

miles in

full doses of

constable. The snake was a cobra of dark grey colour, 3ft. 3ins. long. The lad was brought to the Fyzabad Sudder Dispensary at 7 A.M. On ad-

treated

employed strychnia the results

were

on

The father seized the snake and dashed it some distance away, where it was killed by a police

incised, washed with a strong solution of permanganate of potassium, and a bandage was applied tightly above the ankle. Five minims of the ordinary pharmacopceial solution of strychnia were injected every five minutes with the seventh injection the boy had a tetanic

tioners to adopt it, and McDonald reports a case of snake-bite followed by intestinal haemorrhage and death, which was treated in this way without effect; but states that in two other cases

A.M.

Surgeon-Captain

Hindoo lad who was the great toe by a cobra. a

of any kind. There was no on the great toe and the a mark of the tooth skin was ecchymosed and swollen. The wound

administration should

in this

bitten at 6-30

of

case

mission the

or

until it

patient's safety.

reported

a

if

be suspenThis ded, disappears. may be renewed if the symptoms come on again, when a repetition of the remedy is required to assure the the

and

Surgeon-Major Cadge Pratt

This dose should

collapse continues and if necessary it should be repeated until the twitching of the muscles show the physiological action of strychnia, when

383

but

was

on

at

once

about half

renewed 12

a.m.

at

the

an

hour

When

drowsiness

later the

injections

came were

and between 11 and succession of severe tetanic

longer intervals, boy

had

a

spasms, when the strychnia was discontinued. At 6-30 P.M. the ligature was removed and the

patient made a good recovery. We give in another column a summary of 11 cases which have been treated by hypodermic injection of strychnine. Two were ascertained to

be srenuine cases of cobra-bite, and both recovered; half an hour had elapsed between the time of the bite and the commencement of the treat-

ment; 65 minims in 13 doses

were given in the 4 in doses in the second. minims 60 and first case which recovered cases the kind of In two other

snake

was

Russell's

maining nosis

definitely ascertained,?one being

viper,

the other

a

krait.

In the

a

re-

five which ended in recovery the diaguncertain; while in regard to the two

was

which ended in death nothing was known as to the kind of snake which had inflicted the bite, and an interval of one and-a-half and three

hours,

respectively, elapsed before the commence-

ment of the treatment. The result is undoubtedly encouraging and justifies an extensive trial.

In the Therapeutic Gazette of August 1894) we notice a communication from Dr. Mueller in which he recommends in bad cases an injection of 16 minims of the liquor strych. to be repeated after 15 minutes if the does not

improve,

and

a

continuance

(B. P.), patient5 of injec-

tions of 8 minims about every 15 minutes until, all symptoms have disappeared or until the

.

INDIAN MEDICAL GAZETTE.

384

physiological effects of the strychnine begins develop. In the worst cases one-fifth to onethird of a grain has been necessary. Dr. Mueller believes that four things are proved: 1. That strychnine acts regularly and promptly. 2. Its to

action

poison

stops entirely after a time. like the poison of fungi,

mussels develops

regularly.

4. The

sometimes remains latent in the

considerable time,

so

parently conquered start

a new course

3. The snakeof fishes

and

snake-poison

system

for

a

that, when it has been apfor a time; it may suddenly

of

symptoms.

recommended that the

It is therefore of

strychnine injections employed until unmistakable symptoms of the snake-poison are perceptible, as the pioison may act so slowly that the patient succumbs to the strychnine before the state which requires and neutralises its action has developed; and secondly, it is recommended that the patient should be watched after the disshould not

be

appearance of the last symptoms for another 24 hours in order to be able to combat in time a sudden

relapse.

[Oct.

1894.

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