577
SLVL is confirmed, the role of other aetiological factors, especially viruses, in lymphomagenesis should be
TABLE I-SITE OF ORAL CANCER ACCORDING TO WHICH SIDE LIME IS APPLIED
investigated. We thank ProfD. Catovsky for reviewing morphology; ProfD. Mason and colleagues for advice on lymphocyte phenotyping; the protein reference laboratory, Queen Mary’s Hospital, Roehampton; and Dr T. Rabbitts and Prof Y. Tsulimoto for the probes. 1. B. is a Wellcome Research Fellow and T. R. a Wellcome University Award Lecturer.
REFERENCES 1. Melo JV, Robinson DSF, Gregory C, Catovsky D. Splenic B cell lymphoma with "villous" lymphocytes in the peripheral blood: a disorder distinct from hairy cell leukaemia. Leukaemia 1987; 1: 294-99. 2. Bates I, Bedu-Addo G, Bevan D, Rutherford TR. Use of immunoglobulin gene rearrangements to show clonal lymphoproliferanon in hyper-reactive malarial splenomegaly. Lancet
1991; 337: 505-07. 3. Bates I, Bedu-Addo G, Rutherford TR. Extracting, storing and transporting whole blood DNA under tropical conditions. J Clin Pathol 1991; 44: 605-06. 4. Bennett JM, Catovsky D, Caniel M-T, et al. Proposals for the classification of chronic (mature) B and T lymphoid leukaemias. J Clin Pathol 1989; 42: 567-84. 5. Raffeld M, Jaffe ES. bcl-1, t(11;14), and mantle-cell derived lymphomas. Blood 1991; 78: 259-63. 6. Annotation. The role of bcl-2 gene in lymphoma. Br J Haematol 1990; 75: 449-53. 7. Sonnet J, Michaux JL, Hekster C. Incidence and forms of leukaemia among the Congolese Bantus. Trop Geogr Med 1966; 18: 272-86. 8. Spiriano P, Barosi G, Invenizzi R, et al. Splenomegalic immunocytoma with circulating hairy cells. Haematologica 1986; 71: 25-33.
ADDRESSES: Division of Haematology, St George’s Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK (I. Bates, MB, T. Rutherford, PhD, D. H. Bevan, MRCPath); and Komfo Anokye Teaching Hospital, Kumasi, Ghana (G. Bedu-Addo, MB) Correspondence to Dr Imelda Bates.
Slaked lime and betel nut cancer in Papua New Guinea
The side on which lime is applied differs significantly
SLVL is confirmed, the role of other aetiological factors, especially viruses, in lymphomagenesis should be
TABLE I-SITE OF ORAL CANCER ACCORDING TO WHICH SIDE LIME IS APPLIED
investigated. We thank ProfD. Catovsky for reviewing morphology; ProfD. Mason and colleagues for advice on lymphocyte phenotyping; the protein reference laboratory, Queen Mary’s Hospital, Roehampton; and Dr T. Rabbitts and Prof Y. Tsulimoto for the probes. 1. B. is a Wellcome Research Fellow and T. R. a Wellcome University Award Lecturer.
REFERENCES 1. Melo JV, Robinson DSF, Gregory C, Catovsky D. Splenic B cell lymphoma with "villous" lymphocytes in the peripheral blood: a disorder distinct from hairy cell leukaemia. Leukaemia 1987; 1: 294-99. 2. Bates I, Bedu-Addo G, Bevan D, Rutherford TR. Use of immunoglobulin gene rearrangements to show clonal lymphoproliferanon in hyper-reactive malarial splenomegaly. Lancet
1991; 337: 505-07. 3. Bates I, Bedu-Addo G, Rutherford TR. Extracting, storing and transporting whole blood DNA under tropical conditions. J Clin Pathol 1991; 44: 605-06. 4. Bennett JM, Catovsky D, Caniel M-T, et al. Proposals for the classification of chronic (mature) B and T lymphoid leukaemias. J Clin Pathol 1989; 42: 567-84. 5. Raffeld M, Jaffe ES. bcl-1, t(11;14), and mantle-cell derived lymphomas. Blood 1991; 78: 259-63. 6. Annotation. The role of bcl-2 gene in lymphoma. Br J Haematol 1990; 75: 449-53. 7. Sonnet J, Michaux JL, Hekster C. Incidence and forms of leukaemia among the Congolese Bantus. Trop Geogr Med 1966; 18: 272-86. 8. Spiriano P, Barosi G, Invenizzi R, et al. Splenomegalic immunocytoma with circulating hairy cells. Haematologica 1986; 71: 25-33.
ADDRESSES: Division of Haematology, St George’s Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK (I. Bates, MB, T. Rutherford, PhD, D. H. Bevan, MRCPath); and Komfo Anokye Teaching Hospital, Kumasi, Ghana (G. Bedu-Addo, MB) Correspondence to Dr Imelda Bates.
Slaked lime and betel nut cancer in Papua New Guinea
The side on which lime is applied differs significantly
