Expert Review of Cardiovascular Therapy
ISSN: 1477-9072 (Print) 1744-8344 (Online) Journal homepage: http://www.tandfonline.com/loi/ierk20
Short-term mechanical circulatory support by veno-arterial extracorporeal membrane oxygenation in the management of cardiogenic shock and end-stage heart failure Jasper J Brugts & Kadir Caliskan To cite this article: Jasper J Brugts & Kadir Caliskan (2014) Short-term mechanical circulatory support by veno-arterial extracorporeal membrane oxygenation in the management of cardiogenic shock and end-stage heart failure, Expert Review of Cardiovascular Therapy, 12:2, 145-153, DOI: 10.1586/14779072.2014.880051 To link to this article: http://dx.doi.org/10.1586/14779072.2014.880051
Published online: 13 Jan 2014.
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Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=ierk20 Download by: [UC Santa Barbara Library]
Date: 24 July 2017, At: 10:37
THEMED ARTICLE y Heart Failure
Special Report
Short-term mechanical circulatory support by veno-arterial extracorporeal membrane oxygenation in the management of cardiogenic shock and end-stage heart failure Expert Rev. Cardiovasc. Ther. 12(2), 145–153 (2014)
Jasper J Brugts*1 and Kadir Caliskan1,2 1 Department of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands 2 Department of Advance Heart Failure and Transplantation Unit, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands *Author for correspondence: [email protected]
Despite modern treatment modalities, cardiogenic shock is associated with a very high risk of mortality and morbidity. The short- and long-term survival in patients with cardiogenic shock or end-stage heart failure has improved considerably by recent technological advances in short and long-term mechanical circulatory support devices. For short-term mechanical support, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used as bridge-to-decision and bridge-to-recovery in cardiogenic shock patients. Long-term mechanical circulatory support devices such as left ventricular assist devices (LVADs) are widely available and play a central role in bridge-to-transplantation in those eligible for heart transplantation (HTX) and as destination therapy (DT) in those not eligible for heart transplantation. Nevertheless, patients with critical cardiogenic shock show a deleterious outcome after LVAD-implantation or HTX with higher mortality, more complications and higher burden on financial resources. These considerations underscore the importance of optimal timing and appropriate patient selection for eventual LVAD therapy. The current report will focus on the immediate management of patients with cardiogenic shock with inotropes, discuss the use of IABP and focus mainly on pivotal choices to be made in the period spanned by short term mechanical circulatory support in patients with refractory cardiogenic shock. KEYWORDS: assist device . cardiogenic shock . ECMO . heart failure . LVAD . mechanical circulatory support
Cardiogenic shock is a critical clinical condition of inadequate tissue perfusion resulting in tissue hypoxia due to severe impairment of cardiac pump function despite adequate amount of blood volume [1]. The clinical criteria for the diagnosis of cardiogenic shock based on the SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK (SHOCK) trial [1] are: a systolic blood pressure
ISSN: 1477-9072 (Print) 1744-8344 (Online) Journal homepage: http://www.tandfonline.com/loi/ierk20
Short-term mechanical circulatory support by veno-arterial extracorporeal membrane oxygenation in the management of cardiogenic shock and end-stage heart failure Jasper J Brugts & Kadir Caliskan To cite this article: Jasper J Brugts & Kadir Caliskan (2014) Short-term mechanical circulatory support by veno-arterial extracorporeal membrane oxygenation in the management of cardiogenic shock and end-stage heart failure, Expert Review of Cardiovascular Therapy, 12:2, 145-153, DOI: 10.1586/14779072.2014.880051 To link to this article: http://dx.doi.org/10.1586/14779072.2014.880051
Published online: 13 Jan 2014.
Submit your article to this journal
Article views: 173
View related articles
View Crossmark data
Citing articles: 4 View citing articles
Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=ierk20 Download by: [UC Santa Barbara Library]
Date: 24 July 2017, At: 10:37
THEMED ARTICLE y Heart Failure
Special Report
Short-term mechanical circulatory support by veno-arterial extracorporeal membrane oxygenation in the management of cardiogenic shock and end-stage heart failure Expert Rev. Cardiovasc. Ther. 12(2), 145–153 (2014)
Jasper J Brugts*1 and Kadir Caliskan1,2 1 Department of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands 2 Department of Advance Heart Failure and Transplantation Unit, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands *Author for correspondence: [email protected]
Despite modern treatment modalities, cardiogenic shock is associated with a very high risk of mortality and morbidity. The short- and long-term survival in patients with cardiogenic shock or end-stage heart failure has improved considerably by recent technological advances in short and long-term mechanical circulatory support devices. For short-term mechanical support, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used as bridge-to-decision and bridge-to-recovery in cardiogenic shock patients. Long-term mechanical circulatory support devices such as left ventricular assist devices (LVADs) are widely available and play a central role in bridge-to-transplantation in those eligible for heart transplantation (HTX) and as destination therapy (DT) in those not eligible for heart transplantation. Nevertheless, patients with critical cardiogenic shock show a deleterious outcome after LVAD-implantation or HTX with higher mortality, more complications and higher burden on financial resources. These considerations underscore the importance of optimal timing and appropriate patient selection for eventual LVAD therapy. The current report will focus on the immediate management of patients with cardiogenic shock with inotropes, discuss the use of IABP and focus mainly on pivotal choices to be made in the period spanned by short term mechanical circulatory support in patients with refractory cardiogenic shock. KEYWORDS: assist device . cardiogenic shock . ECMO . heart failure . LVAD . mechanical circulatory support
Cardiogenic shock is a critical clinical condition of inadequate tissue perfusion resulting in tissue hypoxia due to severe impairment of cardiac pump function despite adequate amount of blood volume [1]. The clinical criteria for the diagnosis of cardiogenic shock based on the SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK (SHOCK) trial [1] are: a systolic blood pressure
