RESEARCH ARTICLE
Sexually dimorphic neuronal responses to social isolation Laura Senst1,2†, Dinara Baimoukhametova1,2†, Toni-Lee Sterley1,2, Jaideep Singh Bains1,2* 1
Department of Physiology and Pharmacology, University of Calgary, Calgary, Canada; 2Hotchkiss Brain Institute, University of Calgary, Calgary, Canada
Abstract Many species use social networks to buffer the effects of stress. The mere absence of a social network, however, may also be stressful. We examined neuroendocrine, PVN CRH neurons and report that social isolation alters the intrinsic properties of these cells in sexually dimorphic fashion. Specifically, isolating preadolescent female mice from littermates for 0.05). Group-housed males subjected to swim have longer FSL than group-housed, naive males (p
Sexually dimorphic neuronal responses to social isolation Laura Senst1,2†, Dinara Baimoukhametova1,2†, Toni-Lee Sterley1,2, Jaideep Singh Bains1,2* 1
Department of Physiology and Pharmacology, University of Calgary, Calgary, Canada; 2Hotchkiss Brain Institute, University of Calgary, Calgary, Canada
Abstract Many species use social networks to buffer the effects of stress. The mere absence of a social network, however, may also be stressful. We examined neuroendocrine, PVN CRH neurons and report that social isolation alters the intrinsic properties of these cells in sexually dimorphic fashion. Specifically, isolating preadolescent female mice from littermates for 0.05). Group-housed males subjected to swim have longer FSL than group-housed, naive males (p
