HHS Public Access Author manuscript Author Manuscript
Stroke. Author manuscript; available in PMC 2017 October 01. Published in final edited form as: Stroke. 2016 October ; 47(10): 2618–2626. doi:10.1161/STROKEAHA.116.013059.
Sex Disparities in Ischemic Stroke Care: The Florida Puerto Rico Collaboration to Reduce Stroke Disparities Study (CReSD)
Author Manuscript
Negar Asdaghi, MD, FRCPC1, Jose G. Romano, MD1, Kefeng Wang, MSc1, Maria A. Ciliberti-Vargas, MPH1, Sebastian Koch, MD1, Hannah Gardener, ScD1, Chuanhui Dong, PhD1, David Z. Rose, MD2, Salina P. Waddy, MD3, Mary Robichaux, MPH, MBA4, Enid J. Garcia, MD, MPH5, Juan A. Gonzalez-Sanchez, MD6, W. Scott Burgin, MD2, Ralph L. Sacco, MD, MS1, and Tatjana Rundek, MD, PhD1 1Department
of Neurology, University of Miami Miller School of Medicine, Miami, Florida of Neurology, University of South Florida School of Medicine, Tampa, Florida 3National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 4The American Heart Association, Greater Southeast Affiliate, Marietta, Georgia 5Endowed Health Services Research Center, University of Puerto Rico School of Medicine, San Juan, Puerto Rico 6Department of Emergency Medicine, University of Puerto Rico School of Medicine, San Juan, Puerto Rico 2Department
Abstract Author Manuscript
Background and Purpose—Sex-specific disparities in stroke care including thrombolytic therapy and early hospital admission is reported. In a large registry of Florida and Puerto Rico hospitals participating in the Get With The Guidelines – Stroke (GWTG-S) program, we sought to determine sex-specific differences in ischemic stroke performance metrics and overall thrombolytic treatment. Methods—51,317 (49% women) patients were included from 73 sites from 2010–2014. Multivariable logistic regression with generalized estimating equations evaluated sex-specific differences in the pre-specified GWTG-S metrics for defect free care (DFC) in ischemic stroke, adjusting for age, race-ethnicity, insurance status, hospital characteristics, individual risk factors and the presenting stroke severity.
Author Manuscript
Results—As compared to men, women were older (73±15 vs. 69±14 years; p
Stroke. Author manuscript; available in PMC 2017 October 01. Published in final edited form as: Stroke. 2016 October ; 47(10): 2618–2626. doi:10.1161/STROKEAHA.116.013059.
Sex Disparities in Ischemic Stroke Care: The Florida Puerto Rico Collaboration to Reduce Stroke Disparities Study (CReSD)
Author Manuscript
Negar Asdaghi, MD, FRCPC1, Jose G. Romano, MD1, Kefeng Wang, MSc1, Maria A. Ciliberti-Vargas, MPH1, Sebastian Koch, MD1, Hannah Gardener, ScD1, Chuanhui Dong, PhD1, David Z. Rose, MD2, Salina P. Waddy, MD3, Mary Robichaux, MPH, MBA4, Enid J. Garcia, MD, MPH5, Juan A. Gonzalez-Sanchez, MD6, W. Scott Burgin, MD2, Ralph L. Sacco, MD, MS1, and Tatjana Rundek, MD, PhD1 1Department
of Neurology, University of Miami Miller School of Medicine, Miami, Florida of Neurology, University of South Florida School of Medicine, Tampa, Florida 3National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 4The American Heart Association, Greater Southeast Affiliate, Marietta, Georgia 5Endowed Health Services Research Center, University of Puerto Rico School of Medicine, San Juan, Puerto Rico 6Department of Emergency Medicine, University of Puerto Rico School of Medicine, San Juan, Puerto Rico 2Department
Abstract Author Manuscript
Background and Purpose—Sex-specific disparities in stroke care including thrombolytic therapy and early hospital admission is reported. In a large registry of Florida and Puerto Rico hospitals participating in the Get With The Guidelines – Stroke (GWTG-S) program, we sought to determine sex-specific differences in ischemic stroke performance metrics and overall thrombolytic treatment. Methods—51,317 (49% women) patients were included from 73 sites from 2010–2014. Multivariable logistic regression with generalized estimating equations evaluated sex-specific differences in the pre-specified GWTG-S metrics for defect free care (DFC) in ischemic stroke, adjusting for age, race-ethnicity, insurance status, hospital characteristics, individual risk factors and the presenting stroke severity.
Author Manuscript
Results—As compared to men, women were older (73±15 vs. 69±14 years; p
