Pediatr Nephrol DOI 10.1007/s00467-015-3113-7
ORIGINAL ARTICLE
Severe neutropenia in children after renal transplantation: incidence, course, and treatment with granulocyte colony-stimulating factor Rachel Becker-Cohen 1 & Efrat Ben-Shalom 1 & Choni Rinat 1 & Sofia Feinstein 1 & Michael Geylis 1 & Yaacov Frishberg 1
Received: 8 January 2015 / Revised: 2 April 2015 / Accepted: 6 April 2015 # IPNA 2015
Abstract Background Infections are an important cause of morbidity and mortality in solid organ transplant recipients. Neutrophils play a crucial role in the initial host defense against bacterial pathogens. Neutropenia is not uncommon after renal transplantation in adults; however, there are scarce published data in children. We conducted a historical cohort study to evaluate the incidence, clinical course, and management of severe neutropenia after renal transplantation in children. Methods In a single-center study, we collected clinical and laboratory data on all children (
ORIGINAL ARTICLE
Severe neutropenia in children after renal transplantation: incidence, course, and treatment with granulocyte colony-stimulating factor Rachel Becker-Cohen 1 & Efrat Ben-Shalom 1 & Choni Rinat 1 & Sofia Feinstein 1 & Michael Geylis 1 & Yaacov Frishberg 1
Received: 8 January 2015 / Revised: 2 April 2015 / Accepted: 6 April 2015 # IPNA 2015
Abstract Background Infections are an important cause of morbidity and mortality in solid organ transplant recipients. Neutrophils play a crucial role in the initial host defense against bacterial pathogens. Neutropenia is not uncommon after renal transplantation in adults; however, there are scarce published data in children. We conducted a historical cohort study to evaluate the incidence, clinical course, and management of severe neutropenia after renal transplantation in children. Methods In a single-center study, we collected clinical and laboratory data on all children (
