Severe acidosis does not predict fatal outcomes in ICU patients - a retrospective analysis Yoav Paz MD, MHA, Alexander Zegerman MD, Patrick Sorkine MD, Idit Matot MD PII: DOI: Reference:
S0883-9441(13)00444-9 doi: 10.1016/j.jcrc.2013.11.007 YJCRC 51370
To appear in:
Journal of Critical Care
Received date: Revised date: Accepted date:
17 September 2013 2 November 2013 10 November 2013
Please cite this article as: Paz Yoav, Zegerman Alexander, Sorkine Patrick, Matot Idit, Severe acidosis does not predict fatal outcomes in ICU patients - a retrospective analysis, Journal of Critical Care (2013), doi: 10.1016/j.jcrc.2013.11.007
This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
1
Cover sheet
Severe acidosis does not predict fatal outcomes in ICU patients - a
RI P
T
retrospective analysis
Yoav Paz, Alexander Zegerman, Patrick Sorkine, Idit Matot
SC
Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky
MA NU
Medical Center, Sackler School of Medicine, Tel Aviv University, Israel.
Yoav Paz MD, MHA
General Intensive Care Unit, Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239
PT
ED
Israel
Alexander Zegerman MD,
CE
General Intensive Care Unit, Department of Anesthesiology, Critical Care and Pain
Israel
AC
Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239
Patrick Sorkine MD, General Intensive Care Unit, Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239 Israel
Idit Matot MD, Chair & Prof, Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239 Israel
ACCEPTED MANUSCRIPT
2
Corresponding author: Idit Matot MD, Chair & Prof, Department of Anesthesiology, Critical Care and Pain Medicine, Tel
RI P
T
Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239 Israel Fax: 97236973026
SC
Tel: 972524262799
MA NU
E-mail: [email protected]
Conflict of interest:
There are no relevant conflicts of interest for all authors.
AC
CE
PT
ED
Word count of the paper: 1802 words
ACCEPTED MANUSCRIPT
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Key words: Acidosis; intensive care; resuscitation; sepsis; survival
Abstract
RI P
T
Purpose:
Severe acidosis is a potentially life-threatening acid – base imbalance. The outcome of patients with severe acidosis has only been anecdotally described. We, therefore,
SC
assessed discharge rate of such patients from the ICU and survival time after the
MA NU
event.
Methods:
A retrospective evaluation of medical records of patients admitted to the ICU of Tel Aviv Medical Center between 2005-2010, in whom arterial blood pH
S0883-9441(13)00444-9 doi: 10.1016/j.jcrc.2013.11.007 YJCRC 51370
To appear in:
Journal of Critical Care
Received date: Revised date: Accepted date:
17 September 2013 2 November 2013 10 November 2013
Please cite this article as: Paz Yoav, Zegerman Alexander, Sorkine Patrick, Matot Idit, Severe acidosis does not predict fatal outcomes in ICU patients - a retrospective analysis, Journal of Critical Care (2013), doi: 10.1016/j.jcrc.2013.11.007
This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
1
Cover sheet
Severe acidosis does not predict fatal outcomes in ICU patients - a
RI P
T
retrospective analysis
Yoav Paz, Alexander Zegerman, Patrick Sorkine, Idit Matot
SC
Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky
MA NU
Medical Center, Sackler School of Medicine, Tel Aviv University, Israel.
Yoav Paz MD, MHA
General Intensive Care Unit, Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239
PT
ED
Israel
Alexander Zegerman MD,
CE
General Intensive Care Unit, Department of Anesthesiology, Critical Care and Pain
Israel
AC
Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239
Patrick Sorkine MD, General Intensive Care Unit, Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239 Israel
Idit Matot MD, Chair & Prof, Department of Anesthesiology, Critical Care and Pain Medicine, Tel Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239 Israel
ACCEPTED MANUSCRIPT
2
Corresponding author: Idit Matot MD, Chair & Prof, Department of Anesthesiology, Critical Care and Pain Medicine, Tel
RI P
T
Aviv Sourasky Medical Center, 6 Weitzman Street, Tel Aviv, 64239 Israel Fax: 97236973026
SC
Tel: 972524262799
MA NU
E-mail: [email protected]
Conflict of interest:
There are no relevant conflicts of interest for all authors.
AC
CE
PT
ED
Word count of the paper: 1802 words
ACCEPTED MANUSCRIPT
3
Key words: Acidosis; intensive care; resuscitation; sepsis; survival
Abstract
RI P
T
Purpose:
Severe acidosis is a potentially life-threatening acid – base imbalance. The outcome of patients with severe acidosis has only been anecdotally described. We, therefore,
SC
assessed discharge rate of such patients from the ICU and survival time after the
MA NU
event.
Methods:
A retrospective evaluation of medical records of patients admitted to the ICU of Tel Aviv Medical Center between 2005-2010, in whom arterial blood pH
