DOI: 10.5301/ijao.5000266
Int J Artif Organs 2014; 37 ( 2): 126 - 132
ORIGINAL ARTICLE
Serum tumor markers in hemodialysis patients Omar Maoujoud1, Samira El Machtani2, Mohammed Asseraji1, Yassine Atbib2, Yassir Zajjari3, Aatif Taoufik3, Elarabi Elbouaiti4, Oualim Zouhair3, Mohammed Benyahia3, Saida Tellal2 Department of Nephrology & Dialysis, 1st Medical & surgical Military Hospital, Agadir - Morocco Department of Biochemistry, Mohammed V Military Hospital, Rabat - Morocco 3 Department of Nephrology & Dialysis, Mohammed V Military Hospital, Faculty of Medicine, Mohammed V - Souissi University, Rabat - Morocco 4 Department of Epidemiology, Mohammed V Military Hospital, Rabat - Morocco 1 2
Aims: The main objective of this work was to evaluate the influence of end-stage renal disease (ESRD) on concentrations of five tumor markers (TMs): carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9 (CA19-9), CA15-3, CA125, and prostate specific antigen (PSA) in a group of chronic hemodialysis patients (CHPs); and to study the influence of hemodialysis (HD) sessions on concentrations of the same TMs. Methods: We compared TMs levels in CHP before HD sessions to a control group of 50 healthy volunteers, the dosages were determined before and immediately after the HD session Comparisons were made before and after correction for dialysis-induced hemoconcentrations. Results: We enrolled 74 CHPs, all TM concentrations were higher in this group compared to control group, but this increase was significant for CEA (4.25 ± 2.89 vs 2.41 ± 1.81ng/ml; p
Int J Artif Organs 2014; 37 ( 2): 126 - 132
ORIGINAL ARTICLE
Serum tumor markers in hemodialysis patients Omar Maoujoud1, Samira El Machtani2, Mohammed Asseraji1, Yassine Atbib2, Yassir Zajjari3, Aatif Taoufik3, Elarabi Elbouaiti4, Oualim Zouhair3, Mohammed Benyahia3, Saida Tellal2 Department of Nephrology & Dialysis, 1st Medical & surgical Military Hospital, Agadir - Morocco Department of Biochemistry, Mohammed V Military Hospital, Rabat - Morocco 3 Department of Nephrology & Dialysis, Mohammed V Military Hospital, Faculty of Medicine, Mohammed V - Souissi University, Rabat - Morocco 4 Department of Epidemiology, Mohammed V Military Hospital, Rabat - Morocco 1 2
Aims: The main objective of this work was to evaluate the influence of end-stage renal disease (ESRD) on concentrations of five tumor markers (TMs): carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9 (CA19-9), CA15-3, CA125, and prostate specific antigen (PSA) in a group of chronic hemodialysis patients (CHPs); and to study the influence of hemodialysis (HD) sessions on concentrations of the same TMs. Methods: We compared TMs levels in CHP before HD sessions to a control group of 50 healthy volunteers, the dosages were determined before and immediately after the HD session Comparisons were made before and after correction for dialysis-induced hemoconcentrations. Results: We enrolled 74 CHPs, all TM concentrations were higher in this group compared to control group, but this increase was significant for CEA (4.25 ± 2.89 vs 2.41 ± 1.81ng/ml; p
