Vol. 41 (6): 1101-1107, November . December, 2015 doi: 10.1590/S1677-5538.IBJU.2014.0460

ORIGINAL ARTICLE

Serum Levels of Trace Elements in Patients with Testicular Cancers _______________________________________________ Mehmet Kaba 1, Necip Pirinççi 1, Mehmet Bilgehan Yüksel 2, İlhan Geçit 1, Mustafa Güneş 1, Murat Demir 1, HurremTuran Akkoyun 3, Halit Demir 4 Department of Urology,Faculty of Medicine,Yuzuncu Yıl University, Van, Turkey; 2 Department of Urology,Faculty of Medicine, Celal Bayar University, Manisa, Turkey; 3 Department of Veterinaryand HealthSciences,Çiçekdağı VocationalCollege, Ahi Evran University, Kırşehir, Turkey; 4 Department of Chemistry, Faculty of Scienceand Art,Yuzuncu Yıl University, Van, Turkey

1

ABSTRACT ARTICLE INFO ______________________________________________________________

______________________

Introduction: Trace elements are primary components of biological structures; however, they can be toxic when their concentrations are higher than those needed for biological functions. Materials and Methods: In the present study serum levels of trace elements were measured in 30 patients (mean age was 26.9±11.2 years) newly diagnosed with germ cell testicular cancer and 32 healthy volunteers (mean age: 27.4±10.8) by using furnace atomic absorption spectrophotometer. Serum samples were stored at-20ºC until assays. Results: In patients with germ cell testicular cancer, the diagnosis was seminoma in 15, mix germ cell tumor in 7, embryonal carcinoma in 4, yolk sac tumor in 2 and teratoma in 2 patients. There was stage I testicular tumor in 19 patients (63.3%) while stage II in 6 patients (20.0%), stage IIIA in 4 patients (13.3%) and stage IIIC in one patient (3.4%). It was found that serum Co, Cu, Mg and Pb levels were increased (p

Serum Levels of Trace Elements in Patients with Testicular Cancers.

Trace elements are primary components of biological structures; however, they can be toxic when their concentrations are higher than those needed for ...
NAN Sizes 0 Downloads 11 Views

Recommend Documents


Serum levels of trace elements and heavy metals in patients with acute hemorrhagic stroke.
Trace elements are essential components of biological structures, but alternatively, they can be toxic at concentrations beyond those necessary for their biological functions. Changes in the concentration of essential trace elements and heavy metals

Analysis of serum levels of 15 trace elements in breast cancer patients in Shandong, China.
Experimental and epidemiological studies suggest that serum levels of trace elements may be associated with breast cancer risk. We compared serum levels of 15 trace elements between breast cancer patients and normal controls from Shandong, China, for

Serum Concentrations of Trace Elements in Patients with Tuberculosis and Its Association with Treatment Outcome.
Deficiencies in essential trace elements are associated with impaired immunity in tuberculosis infection. However, the trace element concentrations in the serum of Korean patients with tuberculosis have not yet been investigated. This study aimed to

Comparison of serum and tissue levels of trace elements in different models of cervical cancer.
Cervical cancer is a leading cause of death by cancer among women worldwide. It is necessary to develop and refine cervical cancer models to more accurately reflect human tumor type. The relevance of cervical cancer to trace element was studied in th

Comparative Study on Serum Levels of 10 Trace Elements in Schizophrenia.
The etiology and pathophysiology of schizophrenia remain obscure. This study explored the associations between schizophrenia risk and serum levels of 10 trace elements. A 1:1 matched case-control study was conducted and matched by age and sex. Blood

Comparing the Levels of Trace Elements in Patients With Diabetic Nephropathy and Healthy Individuals.
Diabetic nephropathy is the most common cause of end stage renal disease (ESRD) in developed countries. Several trace elements were reported to be changed in diabetic nephropathy.

Trace Elements Status in Sera of Patients with Allergic Asthma.
Asthma is a multifactorial disease and its severity varies with the inflammatory grade. There are conflicting reports about the roles of trace elements in asthma. This study examined the effects of zinc (Zn), copper (Cu), and selenium (Se) concentrat

Serum metallothionein in patients with testicular cancer.
Metallothioneins (MTs) have been disclosed as a useful diagnostic factor for tumour progression and drug resistance in a variety of malignancies. Increased levels of MT in blood serum have been found in patients with several types of cancer, but ther

Levels of major and trace elements, including rare earth elements, and ²³⁸U in Croatian tap waters.
Concentrations of 46 elements, including major, trace, and rare earth elements, and (238)U in Croatian tap waters were investigated. Selected sampling locations include tap waters from various hydrogeological regions, i.e., different types of aquifer