Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells.

Periodontal ligament stem cells (PDLSCs) have recently been proposed as a novel option in periodontal regenerative therapy. However, one of the issues...
1MB Sizes 0 Downloads 0 Views

Recommend Documents

Biomechanical force induces the growth factor production in human periodontal ligament-derived cells.
Although many reports have been published on the functional roles of periodontal ligament (PDL) cells, the mechanisms involved in the maintenance and homeostasis of PDL have not been determined. We investigated the effects of biomechanical force on g

Anabolic properties of high mobility group box protein-1 in human periodontal ligament cells in vitro.
High mobility group box protein-1 (HMGB1) is mainly recognized as a chemoattractant for macrophages in the initial phase of host response to pathogenic stimuli. However, recent findings provide evidence for anabolic properties in terms of enhanced pr

Bone morphogenetic protein 7 induces cementogenic differentiation of human periodontal ligament-derived mesenchymal stem cells.
Bone morphogenetic protein 7 (BMP-7) is a multifunctional differentiation factor that belongs to the transforming growth factor superfamily. BMP-7 induces gene expression of protein tyrosine phosphatase-like, member A/cementum attachment protein (PTP

Effects of Activin A on the phenotypic properties of human periodontal ligament cells.
Periodontal ligament (PDL) tissue plays an important role in tooth preservation by structurally maintaining the connection between the tooth root and the bone. The mechanisms involved in the healing and regeneration of damaged PDL tissue, caused by b

Insulin modulates cytokines expression in human periodontal ligament cells.
Periodontal disease (PD) has recently been recognized as the 'sixth' major complication of diabetes but the mechanisms involved in diabetic PD remain unclear. This study was to elucidate the potential bone-sparing effect of insulin in diabetic PD con

Differential Properties of Human ALP+ Periodontal Ligament Stem Cells vs Their ALP- Counterparts.
Characterizing subpopulations of stem cells is important to understand stem cell properties. Tissue-nonspecific alkaline phosphatase (ALP) is associated with mineral tissue forming cells as well as stem cells. Information regarding ALP subpopulation

Semaphorin 3A: an immunoregulator in systemic sclerosis.
Semaphorin 3A (sema3A) plays a regulatory role in immune responses, mainly affecting the activation of regulatory T cells. It has been found to correlate with disease activity in rheumatoid arthritis and systemic lupus erythematosus (SLE). To investi

The immunomodulatory properties of periodontal ligament stem cells isolated from inflamed periodontal granulation.
Periodontitis is currently the main cause of tooth loss and as yet there is no appropriate method for establishing a functional and predictable periodontal regeneration. Tissue engineering involving seed cells provides a new prospect for periodontal

Interaction of enamel matrix proteins with human periodontal ligament cells.
It has recently been shown that enamel matrix derivative (EMD) components (Fraction C, containing 6 kDa peptides (including a leucine-rich amelogenin peptide (LRAP))) differentially regulate osteogenic differentiation of periodontal ligament (PDL) ce