HIV Reports

Virologic Failure Among Children Taking Lopinavir/Ritonavir-containing First-line Antiretroviral Therapy in South Africa Tammy Meyers, PhD,* Shobna Sawry, MPH,† Jessica Y. Wong, MPH,‡ Harry Moultrie, MPH,† Francoise Pinillos, MD,†§ Lee Fairlie, MD,† and Gert van Zyl, PhD¶ Objective: To report the outcomes, clinical management decisions and results of resistance testing among a group of children who developed virologic failure on first-line lopinavir/ritonavir (LPV/r)-based therapy from a large cohort of antiretroviral therapy–treated children in Soweto. Design: Historical cohort study. Methods: Children with virologic failure were identified from a group of 1692 children

ritonavir-containing first-line antiretroviral therapy in South Africa.

To report the outcomes, clinical management decisions and results of resistance testing among a group of children who developed virologic failure on f...
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