Accepted Manuscript Risk stratification of contrast induced–acute kidney injury after percutaneous coronary intervention: should we finally get rid of procedural variables? Giuseppe Andò, MD PhD, Olimpia Trio, MD PhD, Cesare de Gregorio, MD PII:

S0002-9149(15)01195-9

DOI:

10.1016/j.amjcard.2015.04.034

Reference:

AJC 21137

To appear in:

The American Journal of Cardiology

Received Date: 29 March 2015 Accepted Date: 23 April 2015

Please cite this article as: Andò G, Trio O, de Gregorio C, Risk stratification of contrast induced–acute kidney injury after percutaneous coronary intervention: should we finally get rid of procedural variables?, The American Journal of Cardiology (2015), doi: 10.1016/j.amjcard.2015.04.034. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

ACCEPTED MANUSCRIPT

Risk stratification of contrast induced–acute kidney injury after percutaneous coronary intervention: should we finally get rid of procedural variables?

We read the paper by Inohara et al recently appeared in The American Journal of Cardiology (in press). The Authors developed a pre-procedural risk model for contrast

RI PT

induced-acute kidney injury (CI-AKI) in patients undergoing percutaneous coronary

intervention (PCI) and demonstrated that adding procedural variables to the model does not significantly changes discrimination (C-statistics improving from 0.789 to 0.799). With this study the Authors support our previous efforts1 aimed at identifying pre-procedural variables

SC

associated with the risk of CI-AKI in patients undergoing primary PCI. It is crucial indeed to have a meaningful risk stratification at baseline that proves to be independent from

M AN U

subsequent procedural variables, which hardly can be anticipated at clinical presentation. Two points deserve in our view a specific comment. First, in the study by Inohara et al the use of radial access, as compared to femoral, was significantly associated with a reduced incidence of CI-AKI (radial approach was used in 24% of patients experiencing CI-AKI, as compared to 38% in patients not experiencing, p

Risk stratification of contrast-induced acute kidney injury after percutaneous coronary intervention: should we finally get rid of procedural variables?

Risk stratification of contrast-induced acute kidney injury after percutaneous coronary intervention: should we finally get rid of procedural variables? - PDF Download Free
186KB Sizes 2 Downloads 6 Views