Gut and Liver, Vol. 11, No. 3, May 2017, pp. 363-369
ORiginal Article
Risk Factors for Vitamin D, Zinc, and Selenium Deficiencies in Korean Patients with Inflammatory Bowel Disease Yoo Min Han1,2, Hyuk Yoon3, Soo Lim3, Mi-Kyung Sung4, Cheol Min Shin3, Young Soo Park3, Nayoung Kim1,3, Dong Ho Lee1,3, and Joo Sung Kim1,2 1 Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 2Department of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 3Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, and 4Department of Food and Nutrition, Sookmyung Women’s University, Seoul, Korea
See editorial on page 317. Background/Aims: Studies on the micronutrient status of Asian patients with inflammatory bowel disease (IBD) are scarce. We evaluated the prevalence of micronutrient deficiency and verified the risk factors for micronutrient deficiency in Korean patients with IBD. Methods: We measured the serum levels of 25-hydroxyvitamin D3 [25-(OH)D], zinc, and selenium to analyze the clinical risk factors for micronutrient levels below the reference values. In addition, we compared the 25-(OH)D levels of patients with IBD to those of age- and sex-matched healthy controls. Results: Among the 83 patients, 74 (89.2%) had suboptimal serum 25-(OH)D levels. The mean plasma 25-(OH)D level in patients with IBD was significantly reduced compared to that of the healthy controls (12.3±6.2 ng/mL vs 20.0±6.7 ng/mL; p
ORiginal Article
Risk Factors for Vitamin D, Zinc, and Selenium Deficiencies in Korean Patients with Inflammatory Bowel Disease Yoo Min Han1,2, Hyuk Yoon3, Soo Lim3, Mi-Kyung Sung4, Cheol Min Shin3, Young Soo Park3, Nayoung Kim1,3, Dong Ho Lee1,3, and Joo Sung Kim1,2 1 Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 2Department of Internal Medicine and Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, 3Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, and 4Department of Food and Nutrition, Sookmyung Women’s University, Seoul, Korea
See editorial on page 317. Background/Aims: Studies on the micronutrient status of Asian patients with inflammatory bowel disease (IBD) are scarce. We evaluated the prevalence of micronutrient deficiency and verified the risk factors for micronutrient deficiency in Korean patients with IBD. Methods: We measured the serum levels of 25-hydroxyvitamin D3 [25-(OH)D], zinc, and selenium to analyze the clinical risk factors for micronutrient levels below the reference values. In addition, we compared the 25-(OH)D levels of patients with IBD to those of age- and sex-matched healthy controls. Results: Among the 83 patients, 74 (89.2%) had suboptimal serum 25-(OH)D levels. The mean plasma 25-(OH)D level in patients with IBD was significantly reduced compared to that of the healthy controls (12.3±6.2 ng/mL vs 20.0±6.7 ng/mL; p
