Valvular heart disease
Risk and outcomes of aortic valve endocarditis among patients with bicuspid and tricuspid aortic valves Yuka Kiyota,1 Alessandro Della Corte,2 Vanessa Montiero Vieira,1 Karam Habchi,1 Chuan-Chin Huang,1 Ester E Della Ratta,2 Thoralf M Sundt,3 Prem Shekar,4 Jochen D Muehlschlegel,1 Simon C Body1
To cite: Kiyota Y, Della Corte A, Montiero Vieira V, et al. Risk and outcomes of aortic valve endocarditis among patients with bicuspid and tricuspid aortic valves. Open Heart 2017;4:e000545. doi:10.1136/ openhrt-2016-000545
ABSTRACT
Objective Patients with structural abnormalities of cardiac valves, including bicuspid aortic valve (BAV), are said to be at higher risk of infective endocarditis (IE). We sought to determine the risk of IE of the BAV compared with the tricuspid aortic valve (TAV) and to determine the risk of aortic valve replacement and mortality after IE. Methods From medical records of two US and one Italian hospitals, patients with their first episode of IE Received 5 October 2016 of any native valve were identified. In the US cohort 42 Revised 16 March 2017 patients with BAV and 393 patients with TAV with IE Accepted 21 March 2017 occurring between 1 January 2000 and 30 June 2014 were identified. In the Italian cohort 48 patients with BAV and 341 patients with TAV with IE underwent valve replacement surgery between 1 January 2000 and1 November 2015. The risk of IE for BAV and TAV and subsequent outcomes were determined after matching to patients without IE. Results After adjustment for risk factors, the risk of IE in the US cohort was 23.1 (95% CI 8.1 to 100, p
Risk and outcomes of aortic valve endocarditis among patients with bicuspid and tricuspid aortic valves Yuka Kiyota,1 Alessandro Della Corte,2 Vanessa Montiero Vieira,1 Karam Habchi,1 Chuan-Chin Huang,1 Ester E Della Ratta,2 Thoralf M Sundt,3 Prem Shekar,4 Jochen D Muehlschlegel,1 Simon C Body1
To cite: Kiyota Y, Della Corte A, Montiero Vieira V, et al. Risk and outcomes of aortic valve endocarditis among patients with bicuspid and tricuspid aortic valves. Open Heart 2017;4:e000545. doi:10.1136/ openhrt-2016-000545
ABSTRACT
Objective Patients with structural abnormalities of cardiac valves, including bicuspid aortic valve (BAV), are said to be at higher risk of infective endocarditis (IE). We sought to determine the risk of IE of the BAV compared with the tricuspid aortic valve (TAV) and to determine the risk of aortic valve replacement and mortality after IE. Methods From medical records of two US and one Italian hospitals, patients with their first episode of IE Received 5 October 2016 of any native valve were identified. In the US cohort 42 Revised 16 March 2017 patients with BAV and 393 patients with TAV with IE Accepted 21 March 2017 occurring between 1 January 2000 and 30 June 2014 were identified. In the Italian cohort 48 patients with BAV and 341 patients with TAV with IE underwent valve replacement surgery between 1 January 2000 and1 November 2015. The risk of IE for BAV and TAV and subsequent outcomes were determined after matching to patients without IE. Results After adjustment for risk factors, the risk of IE in the US cohort was 23.1 (95% CI 8.1 to 100, p
