The New England Journal of Medicine Downloaded from nejm.org at CARLETON UNIVERSITY on November 18, 2015. For personal use only. No other uses without permission. From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

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The New England Journal of Medicine Downloaded from nejm.org at CARLETON UNIVERSITY on November 18, 2015. For personal use only. No other uses without...
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