RESPONSE OF OVINE PANCREATIC AMYLASE BLOOD GLUCOSE 1
TO ELEVATED
J. L. Call, G. E. Mitchell, Jr. and C. O. Little
SUMMARY Response of pancreatic amylase to blood glucose was studied in wethers with re-entrant cannulae of the common bile duct. Combined biliary and pancreatic secretions were collected and assayed for amylase activity by a starchiodine procedure before and after single intravenous injections of glucose or intravenous infusion of glucose for 3 hr out of each 12 for 3 or 7 days. Single injections containing 5 to 8 g of glucose or infusion of .5 ml per min of 8% glucose failed to significantly alter amylase secretion. Infusion of 16% glucose (.5 or 1 ml per min) sharply reduced amylase secretion (P
TO ELEVATED
J. L. Call, G. E. Mitchell, Jr. and C. O. Little
SUMMARY Response of pancreatic amylase to blood glucose was studied in wethers with re-entrant cannulae of the common bile duct. Combined biliary and pancreatic secretions were collected and assayed for amylase activity by a starchiodine procedure before and after single intravenous injections of glucose or intravenous infusion of glucose for 3 hr out of each 12 for 3 or 7 days. Single injections containing 5 to 8 g of glucose or infusion of .5 ml per min of 8% glucose failed to significantly alter amylase secretion. Infusion of 16% glucose (.5 or 1 ml per min) sharply reduced amylase secretion (P
