Scand J Clin Lab Invest 1992; 52: 159-167
Response of diastolic blood pressure to long-term sodium restriction is posture related A . M . J U L A , T . E. R O N N E M A A , S. J . P I H A & J . P. M A K I
Scand J Clin Lab Invest Downloaded from informahealthcare.com by Nyu Medical Center on 01/07/15 For personal use only.
Rehabilitation Research Centre of the Social Insurance Institution, Turku, Finland
Jula A M , Ronnemaa T E , Piha SJ, Maki JP. Response of diastolic blood pressure to long-term sodium restriction is posture related. Scand J Clin Lab Invest 1992: 52: 159-167. Eighty-five subjects, aged 3 1-55 years, suffering from uncomplicated essential hypertension and receiving no regular medication were randomized to sodium restriction and control groups. Systolic (SBP) and diastolic (DBP) blood pressure were measured during an orthostatic test at baseline and after 6 months sodium restriction. The mean daily sodium excretion of 43 treated subjects decreased from 193+91 mmol to 95+70 mmol (ptO.OO1). Treated patients were divided on the basis of their mean overall out-patient clinic (OC) D B P decrease in the sitting position during the 6 months (monthly measurements) into sodium-sensitive (DBP decrease > 1 0 mmHg, n= 17), indeterminate (DBP decrease 5-10 mmHg, n=18) and sodium-resistant (DBP decrease t 5 mmHg, n=8) subgroups. At 6 months the level of D B P in the supine position was lower than at baseline in both sensitive and resistant subgroups, whereas in the standing position a lower DBP than at baseline was seen only in the sodiumsensitive subgroup. The magnitude of the subsequent OC D B P decrease was significantly associated with a high baseline seated OC D B P (p
Response of diastolic blood pressure to long-term sodium restriction is posture related A . M . J U L A , T . E. R O N N E M A A , S. J . P I H A & J . P. M A K I
Scand J Clin Lab Invest Downloaded from informahealthcare.com by Nyu Medical Center on 01/07/15 For personal use only.
Rehabilitation Research Centre of the Social Insurance Institution, Turku, Finland
Jula A M , Ronnemaa T E , Piha SJ, Maki JP. Response of diastolic blood pressure to long-term sodium restriction is posture related. Scand J Clin Lab Invest 1992: 52: 159-167. Eighty-five subjects, aged 3 1-55 years, suffering from uncomplicated essential hypertension and receiving no regular medication were randomized to sodium restriction and control groups. Systolic (SBP) and diastolic (DBP) blood pressure were measured during an orthostatic test at baseline and after 6 months sodium restriction. The mean daily sodium excretion of 43 treated subjects decreased from 193+91 mmol to 95+70 mmol (ptO.OO1). Treated patients were divided on the basis of their mean overall out-patient clinic (OC) D B P decrease in the sitting position during the 6 months (monthly measurements) into sodium-sensitive (DBP decrease > 1 0 mmHg, n= 17), indeterminate (DBP decrease 5-10 mmHg, n=18) and sodium-resistant (DBP decrease t 5 mmHg, n=8) subgroups. At 6 months the level of D B P in the supine position was lower than at baseline in both sensitive and resistant subgroups, whereas in the standing position a lower DBP than at baseline was seen only in the sodiumsensitive subgroup. The magnitude of the subsequent OC D B P decrease was significantly associated with a high baseline seated OC D B P (p
