International Journal of
Environmental Research and Public Health Article
Residential Proximity to Major Roadways Is Not Associated with Cardiac Function in African Americans: Results from the Jackson Heart Study Anne M. Weaver 1, *, Gregory A. Wellenius 2 , Wen-Chih Wu 2 , DeMarc A. Hickson 3 , Masoor Kamalesh 4 and Yi Wang 1 1 2 3 4
*
Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN 46202, USA; [email protected] School of Public Health, Brown University, Providence, RI 02903, USA; [email protected] (G.A.W.); [email protected] (W.-C.W.) School of Public Health, Jackson State University, Jackson, MS 39217, USA; [email protected] Richard L. Roudebush VA Medical Center, Indianapolis, IN 46202, USA; [email protected] Correspondence: [email protected]; Tel.: +1-317-274-2185
Academic Editor: Nelson Gouveia Received: 25 March 2016; Accepted: 6 June 2016; Published: 13 June 2016
Abstract: Cardiovascular disease (CVD), including heart failure, is a major cause of morbidity and mortality, particularly among African Americans. Exposure to ambient air pollution, such as that produced by vehicular traffic, is believed to be associated with heart failure, possibly by impairing cardiac function. We evaluated the cross-sectional association between residential proximity to major roads, a marker of long-term exposure to traffic-related pollution, and echocardiographic indicators of left and pulmonary vascular function in African Americans enrolled in the Jackson Heart Study (JHS): left ventricular ejection fraction, E-wave velocity, isovolumic relaxation time, left atrial diameter index, and pulmonary artery systolic pressure. We examined these associations using multivariable linear or logistic regression, adjusting for potential confounders. Of 4866 participants at study enrollment, 106 lived
Environmental Research and Public Health Article
Residential Proximity to Major Roadways Is Not Associated with Cardiac Function in African Americans: Results from the Jackson Heart Study Anne M. Weaver 1, *, Gregory A. Wellenius 2 , Wen-Chih Wu 2 , DeMarc A. Hickson 3 , Masoor Kamalesh 4 and Yi Wang 1 1 2 3 4
*
Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN 46202, USA; [email protected] School of Public Health, Brown University, Providence, RI 02903, USA; [email protected] (G.A.W.); [email protected] (W.-C.W.) School of Public Health, Jackson State University, Jackson, MS 39217, USA; [email protected] Richard L. Roudebush VA Medical Center, Indianapolis, IN 46202, USA; [email protected] Correspondence: [email protected]; Tel.: +1-317-274-2185
Academic Editor: Nelson Gouveia Received: 25 March 2016; Accepted: 6 June 2016; Published: 13 June 2016
Abstract: Cardiovascular disease (CVD), including heart failure, is a major cause of morbidity and mortality, particularly among African Americans. Exposure to ambient air pollution, such as that produced by vehicular traffic, is believed to be associated with heart failure, possibly by impairing cardiac function. We evaluated the cross-sectional association between residential proximity to major roads, a marker of long-term exposure to traffic-related pollution, and echocardiographic indicators of left and pulmonary vascular function in African Americans enrolled in the Jackson Heart Study (JHS): left ventricular ejection fraction, E-wave velocity, isovolumic relaxation time, left atrial diameter index, and pulmonary artery systolic pressure. We examined these associations using multivariable linear or logistic regression, adjusting for potential confounders. Of 4866 participants at study enrollment, 106 lived
