Journal of Analytical Toxicology 2015;39:416 doi:10.1093/jat/bkv034 Advance Access publication April 15, 2015
Letter to the Editor
Reply to Maskell et al We thank the authors for their additional insight regarding the possible source of iso-a-acids (IAA) from alcohol-free beer. The determination of IAA in blood and urine was primarily directed as an alternative approach to that of the traditional alcohol congener analysis (1 – 3). Congeners sourced from the ingredients used in the production of alcoholic beverages provide a complimentary method to existing ones when the source of alcohol is questioned. In these cases ethanol will be invariably detected in one of these fluids with uncertainty over the type and volumes of alcoholic beverage consumed. However, as in any medico-legal matter, a full consideration of the alternative possibilities and the acknowledgment of the method limitations must be considered by the courts.
References 1. Rodda, L.N., Beyer, J., Gerostamoulos, D., Drummer, O.H. (2013) Alcohol congener analysis and the source of alcohol: a review. Forensic Sci Med Path, 9, 194–207. 2. Iffland, R., Jones, A.W. (2003) Evaluating alleged drinking after driving—the hip-flask defence. Part 2. Congener analysis. Med Sci Law, 43, 39 –68. 3. Rodda, L.N., Gerostamoulos, D., Drummer, O.H. (2013) The rapid identification and quantification of iso-a-acids and reduced iso-a-acids in blood using UHPLC-MS/MS: validation of a novel marker for beer consumption. Anal Bioanal Chem, 405, 9755–9767.
Luke N. Rodda, Dimitri Gerostamoulos and Olaf H. Drummer* Department of Forensic Medicine, Monash University and Victorian Institute of Forensic Medicine, 65 Kavanagh St, Melbourne 3006, Australia *Email: [email protected]
# The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected]
Copyright of Journal of Analytical Toxicology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use.
Letter to the Editor
Reply to Maskell et al We thank the authors for their additional insight regarding the possible source of iso-a-acids (IAA) from alcohol-free beer. The determination of IAA in blood and urine was primarily directed as an alternative approach to that of the traditional alcohol congener analysis (1 – 3). Congeners sourced from the ingredients used in the production of alcoholic beverages provide a complimentary method to existing ones when the source of alcohol is questioned. In these cases ethanol will be invariably detected in one of these fluids with uncertainty over the type and volumes of alcoholic beverage consumed. However, as in any medico-legal matter, a full consideration of the alternative possibilities and the acknowledgment of the method limitations must be considered by the courts.
References 1. Rodda, L.N., Beyer, J., Gerostamoulos, D., Drummer, O.H. (2013) Alcohol congener analysis and the source of alcohol: a review. Forensic Sci Med Path, 9, 194–207. 2. Iffland, R., Jones, A.W. (2003) Evaluating alleged drinking after driving—the hip-flask defence. Part 2. Congener analysis. Med Sci Law, 43, 39 –68. 3. Rodda, L.N., Gerostamoulos, D., Drummer, O.H. (2013) The rapid identification and quantification of iso-a-acids and reduced iso-a-acids in blood using UHPLC-MS/MS: validation of a novel marker for beer consumption. Anal Bioanal Chem, 405, 9755–9767.
Luke N. Rodda, Dimitri Gerostamoulos and Olaf H. Drummer* Department of Forensic Medicine, Monash University and Victorian Institute of Forensic Medicine, 65 Kavanagh St, Melbourne 3006, Australia *Email: [email protected]
# The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected]
Copyright of Journal of Analytical Toxicology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use.
