Medical and Pediatric Oncology 20:489496 (1 992)

Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor in Children With Chemotherapy-Induced Neutropenia Ulla M. Saarinen,

MD,

Liisa Hovi, MD, Pekka Riikonen, MD, Jaana Pihkala, and Eeva Juvonen, MD

MD,

groups GM-CSF accelerated myeloid recovTwenty children 1-17 (median, 5.5) years ery, which was preceded by the appearance of age received GM-CSF during chemotherapy-induced neutropenia at the dose of 5 of immature myeloid elements in bone marrow. The ANC levels of 200, 500, and 1,000 bg/kg/day, continued until the absolute neuxlO’/Iiter were exceeded 2,3 (P

Recombinant human granulocyte-macrophage colony-stimulating factor in children with chemotherapy-induced neutropenia.

Twenty children 1-17 (median, 5.5) years of age received GM-CSF during chemotherapy-induced neutropenia at the dose of 5 micrograms/kg/day, continued ...
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