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Recent A rticles in E xperim ental Ageing Research List No. 19, collected January-May 1976 As a regular feature of Gerontology, the Editors publish a selection of recent articles in all fields of ageing research covered in the section on Experimental Gerontology of this journal, appearing in other journals in this general field and in journals covered by the Life Sciences Edition of Current Contents. This selection does not intend to be complete, but to present articles which, in the opinion of the Editors, will be of interest to our readers. The Editors alone are responsible for the selection, and invite readers to bring to their attention articles which they think should be included in the next list. The articles are ordered alphabetically by the first author under the following subject headings: (1) General, (2) Biochemistry, (3) Metabolism, (4) Cell Culture, (5) Physiology and Cell Biology, (6) Immunology, (7) Histology, Cytology and Comparative Anatomy, (8) Pharmacology, (9) Longevity, Populations and Genetics, (10) Plants, and (11) Experi mental Psychology and Behaviour. Biochemistry Gottlieb, D. and Sharma, V.D.: Changes in ribonuclease with age in the fungus Rhizoctonia solani. Mech. Age. Dev. 5: 25-32 (1976). Grinna, L.S. and Barber, A.A.: Kinetic analysis of the age-related differences in glucose-6phosphatase activity. Expl. Gerontol. 10: 352-332 (1975). Massie, H.R. and Baird, M.B.: Catalase levels in Drosophila and the lack of induction by hypolipidemic compounds. A brief note. Mech. Age. Dev. 5.~ 39-44 (1976). Munkres, K.D. and Minssen, M.: Ageing of Neurospora crassa. 1. Evidence for the free radical theory of ageing from studies of a natural-death mutant. Mech. Age. Dev. 5: 79-98(1976). Munkres, K.D. and Colvin, H.J.: Ageing of Neurospora crassa. II. Organic hydroperoxide toxicity and the protective role of antioxidant and the antioxygenic enzymes. Mech. Age. Dev. 5: 99-108(1976). Murai, A.: Miyahara, T., and Shiozawa, S.: Age-related variations in glycosylation of hydroxylysine in human rat skin collagens. Biochim. biophys. Acta 404: 345 (1975). Roman Palacios, R. and Sanchez de Jimenez, E.: Physico-chemical characteristics of ribo somes in relation to cell aging. Biochem. biophys. Res. Commun. 66: 1243-1250 (1975). Rothstein, M.: Aging and the alterations of enzymes. A review. Mech. Age. Dev. 4: 325338 (1975). Rymaszewski, Z.J.; Subbiah, M.T.R., and Kottke, B.A.: Effect of age on sterols and steryl esters in pigeon skin and aorta. Expl. Gerontol. 10: 313-318 (1975). Stevens, C.; Goldblatt, M.J., and Freedman, J.C.: Lack of erythrocyte superoxide dismutase change during human senescence. Mech. Age. Dev. 4: 415-422 (1975). Zs.-Nagy, I. and Zs.-Nagy, V.: Age-dependence of heat-induced strand separation of DNA in situ in postmitotic cells of rat brain as revealed by acridine orange microfluorometry. Mech. Age. Dev. 4: 349-360 (1975).
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Metabolism Berg, A. and Zimmerman, I.D.: Effects of electrical stimulation and norepinephrine on cyclic-AMP levels in the cerebral cortex of the aging rat. Mech. Age. Dev. 4: 377-384 (1975).
Cell Culture Good, P.I.: Aging in mammalian cell populations. A review. Mech. Age. Dev. 4: 339-348 (1975) . Hart, R. W. and Setlow, R.B.: DNA repair in late-passage human cells. Mech. Age. Dev. 5: 67 (1976) . Kruisbeek, A.M.: Age-related changes in ConA- and LPS-induced lymphocyte transforma tion. 1. Effect of culture conditions on mitogen responses of blood and spleen lympho cytes from young and aged rats. Mech. Age. Dev. 5: 125-138 (1976). Mitsui, Y. and Schneider, E.L.: Relationship between cell replication and volume in senes cent human diploid fibroblasts. Mech. Age. Dev. 5: 45-56 (1976). Schneider, E.L.: Mitsui, Y.; Tice, R.; Shorr, S.S., and Braunschweiger, K.: Alteration in cellular RNAs during the in vitro life span of cultured human diploid fibroblasts. II. Synthesis and processing of RNA. Mech. Age. Dev. 4: 449-458 (1975). Sundararaman, V. and Cummings, D.J. : Morphological changes in aging cell lines of Para mecium aurelia. 1. Alterations in the cytoplasm. Mech. Age. Dev. 5: 139-154 (1976).
Physiology and Cell Biology Aschheim, P.: A biological ageing-test for the hypothalamo-hypophysial regulation of the estrous cycle in the rat; in Dorner Endocrinology of sex, pp. 352-358 (Barth, Leipzig, 1974). Aschheim, P.: Effets de l’administration chronique de stéroïdes anticonceptionnels sur l’âge biologique des cycles ovariens après arrêt du traitement. Ann. Biol. anim. Biochim. Biophys. 15: 775-783 (1975). Aschheim, P. et Latouche, J.: Les effets du séjour au froid sur le cycle ovarien de la ratte et son âge biologique; dans Klotz Problèmes actuels d’endocrinologie et de nutrition, vol. 19, pp. 95-110 (1975). Kunz, J. and Keim, U.: On the regeneration of aortic endothelium at different ages. Mech. Age. Dev. 4: 361-370 (1975). Segall, P.E. and Timiras, P.S.: Pathophysiologic findings after chronic tryptophan deficiency in rats. A model for delayed growth and aging. Mech. Age. Dev. 5: 109-124 (1976). Sencar-Cupovic, 1. and Milkovic, S.: The development of sex differences in the adrenal morphology and responsiveness in stress of rats from birth to the end of life. Mech. Age. Dev. 5: 1-10(1976).
Histology, Cytology and Comparative Anatomy Davies, 1. and King, P.E.: A morphometric and cytochemical analysis of aging changes in the flight muscle of Nasonia vitripennis (Walk.) (Hymenoptera, Ptcromalidae). Mech. Age. Dev. 4: 459-468(1975).
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Geinisman, Y. and Bondareff, W.: Decrease in the number of synapses in the semescent brain. A quantitative electron microscopic analysis of the dentate gyrus molecular layer in the rat. Mech. Age. Dev. 5: 11 -2 4 (1976). Ives, P.J.; Haensly, W.E.; Maxwell, P.A., and McArthur, N.H.: A histochemical and ultrastructural study of lipofuscin accumulation in thyroid follicular cells of aging domestic cats. Mech. Age. Dev. 4: 399-414 (1975). Leonard, A. and Leonard, E.D.: Ageing and chromosome aberrations in male mammalian germ cells. Expl Gerontol. 10: 309-312 (1975). Pieri, C.; Zs.-Nagy, /.; Giuli, C., and Mazzufferi, G.: The ageing of rat liver as revealed by electron microscopic morphometry. II. Parameters of regenerated old liver. Expl Gerontol. 10: 341-350(1975). Sames, K.: Histochemical studies on the distribution of acidic glycosaminoglycans in human rib cartilage during the aging process. Mech. Age. Dev. 4: 431-448 (1975). Sato, F.: Tsuchihashi, S., and Kawashima, N.: Age changes in number and size of the murine renal glomeruli. Expl Gerontol. 10: 325-332 (1975).
Pharmacology Estler, C.J.: Dependence on age of metamphetamine-produced changes in thermoregulation and metabolism. Experientia, Basel 31: 1436-1437 (1975).
Longevity, Populations and Genetics Iximb, M.J.: Age-related differences in the water content of normal and irradiated Dro sophila melanogaster. Expl Gerontol. 10: 351 (1975). Reggi, M.L. de: Environmental temperature, X-irradiation and ageing in insects. Expl Gerontol. 10: 333-340 (1975). Ross, M.H. and Bras, G.: Food preference and length of life. Science 190: 165-167 (1975).
Recent A rticles in E xperim ental Ageing Research List No. 19, collected January-May 1976 As a regular feature of Gerontology, the Editors publish a selection of recent articles in all fields of ageing research covered in the section on Experimental Gerontology of this journal, appearing in other journals in this general field and in journals covered by the Life Sciences Edition of Current Contents. This selection does not intend to be complete, but to present articles which, in the opinion of the Editors, will be of interest to our readers. The Editors alone are responsible for the selection, and invite readers to bring to their attention articles which they think should be included in the next list. The articles are ordered alphabetically by the first author under the following subject headings: (1) General, (2) Biochemistry, (3) Metabolism, (4) Cell Culture, (5) Physiology and Cell Biology, (6) Immunology, (7) Histology, Cytology and Comparative Anatomy, (8) Pharmacology, (9) Longevity, Populations and Genetics, (10) Plants, and (11) Experi mental Psychology and Behaviour. Biochemistry Gottlieb, D. and Sharma, V.D.: Changes in ribonuclease with age in the fungus Rhizoctonia solani. Mech. Age. Dev. 5: 25-32 (1976). Grinna, L.S. and Barber, A.A.: Kinetic analysis of the age-related differences in glucose-6phosphatase activity. Expl. Gerontol. 10: 352-332 (1975). Massie, H.R. and Baird, M.B.: Catalase levels in Drosophila and the lack of induction by hypolipidemic compounds. A brief note. Mech. Age. Dev. 5.~ 39-44 (1976). Munkres, K.D. and Minssen, M.: Ageing of Neurospora crassa. 1. Evidence for the free radical theory of ageing from studies of a natural-death mutant. Mech. Age. Dev. 5: 79-98(1976). Munkres, K.D. and Colvin, H.J.: Ageing of Neurospora crassa. II. Organic hydroperoxide toxicity and the protective role of antioxidant and the antioxygenic enzymes. Mech. Age. Dev. 5: 99-108(1976). Murai, A.: Miyahara, T., and Shiozawa, S.: Age-related variations in glycosylation of hydroxylysine in human rat skin collagens. Biochim. biophys. Acta 404: 345 (1975). Roman Palacios, R. and Sanchez de Jimenez, E.: Physico-chemical characteristics of ribo somes in relation to cell aging. Biochem. biophys. Res. Commun. 66: 1243-1250 (1975). Rothstein, M.: Aging and the alterations of enzymes. A review. Mech. Age. Dev. 4: 325338 (1975). Rymaszewski, Z.J.; Subbiah, M.T.R., and Kottke, B.A.: Effect of age on sterols and steryl esters in pigeon skin and aorta. Expl. Gerontol. 10: 313-318 (1975). Stevens, C.; Goldblatt, M.J., and Freedman, J.C.: Lack of erythrocyte superoxide dismutase change during human senescence. Mech. Age. Dev. 4: 415-422 (1975). Zs.-Nagy, I. and Zs.-Nagy, V.: Age-dependence of heat-induced strand separation of DNA in situ in postmitotic cells of rat brain as revealed by acridine orange microfluorometry. Mech. Age. Dev. 4: 349-360 (1975).
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Metabolism Berg, A. and Zimmerman, I.D.: Effects of electrical stimulation and norepinephrine on cyclic-AMP levels in the cerebral cortex of the aging rat. Mech. Age. Dev. 4: 377-384 (1975).
Cell Culture Good, P.I.: Aging in mammalian cell populations. A review. Mech. Age. Dev. 4: 339-348 (1975) . Hart, R. W. and Setlow, R.B.: DNA repair in late-passage human cells. Mech. Age. Dev. 5: 67 (1976) . Kruisbeek, A.M.: Age-related changes in ConA- and LPS-induced lymphocyte transforma tion. 1. Effect of culture conditions on mitogen responses of blood and spleen lympho cytes from young and aged rats. Mech. Age. Dev. 5: 125-138 (1976). Mitsui, Y. and Schneider, E.L.: Relationship between cell replication and volume in senes cent human diploid fibroblasts. Mech. Age. Dev. 5: 45-56 (1976). Schneider, E.L.: Mitsui, Y.; Tice, R.; Shorr, S.S., and Braunschweiger, K.: Alteration in cellular RNAs during the in vitro life span of cultured human diploid fibroblasts. II. Synthesis and processing of RNA. Mech. Age. Dev. 4: 449-458 (1975). Sundararaman, V. and Cummings, D.J. : Morphological changes in aging cell lines of Para mecium aurelia. 1. Alterations in the cytoplasm. Mech. Age. Dev. 5: 139-154 (1976).
Physiology and Cell Biology Aschheim, P.: A biological ageing-test for the hypothalamo-hypophysial regulation of the estrous cycle in the rat; in Dorner Endocrinology of sex, pp. 352-358 (Barth, Leipzig, 1974). Aschheim, P.: Effets de l’administration chronique de stéroïdes anticonceptionnels sur l’âge biologique des cycles ovariens après arrêt du traitement. Ann. Biol. anim. Biochim. Biophys. 15: 775-783 (1975). Aschheim, P. et Latouche, J.: Les effets du séjour au froid sur le cycle ovarien de la ratte et son âge biologique; dans Klotz Problèmes actuels d’endocrinologie et de nutrition, vol. 19, pp. 95-110 (1975). Kunz, J. and Keim, U.: On the regeneration of aortic endothelium at different ages. Mech. Age. Dev. 4: 361-370 (1975). Segall, P.E. and Timiras, P.S.: Pathophysiologic findings after chronic tryptophan deficiency in rats. A model for delayed growth and aging. Mech. Age. Dev. 5: 109-124 (1976). Sencar-Cupovic, 1. and Milkovic, S.: The development of sex differences in the adrenal morphology and responsiveness in stress of rats from birth to the end of life. Mech. Age. Dev. 5: 1-10(1976).
Histology, Cytology and Comparative Anatomy Davies, 1. and King, P.E.: A morphometric and cytochemical analysis of aging changes in the flight muscle of Nasonia vitripennis (Walk.) (Hymenoptera, Ptcromalidae). Mech. Age. Dev. 4: 459-468(1975).
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Geinisman, Y. and Bondareff, W.: Decrease in the number of synapses in the semescent brain. A quantitative electron microscopic analysis of the dentate gyrus molecular layer in the rat. Mech. Age. Dev. 5: 11 -2 4 (1976). Ives, P.J.; Haensly, W.E.; Maxwell, P.A., and McArthur, N.H.: A histochemical and ultrastructural study of lipofuscin accumulation in thyroid follicular cells of aging domestic cats. Mech. Age. Dev. 4: 399-414 (1975). Leonard, A. and Leonard, E.D.: Ageing and chromosome aberrations in male mammalian germ cells. Expl Gerontol. 10: 309-312 (1975). Pieri, C.; Zs.-Nagy, /.; Giuli, C., and Mazzufferi, G.: The ageing of rat liver as revealed by electron microscopic morphometry. II. Parameters of regenerated old liver. Expl Gerontol. 10: 341-350(1975). Sames, K.: Histochemical studies on the distribution of acidic glycosaminoglycans in human rib cartilage during the aging process. Mech. Age. Dev. 4: 431-448 (1975). Sato, F.: Tsuchihashi, S., and Kawashima, N.: Age changes in number and size of the murine renal glomeruli. Expl Gerontol. 10: 325-332 (1975).
Pharmacology Estler, C.J.: Dependence on age of metamphetamine-produced changes in thermoregulation and metabolism. Experientia, Basel 31: 1436-1437 (1975).
Longevity, Populations and Genetics Iximb, M.J.: Age-related differences in the water content of normal and irradiated Dro sophila melanogaster. Expl Gerontol. 10: 351 (1975). Reggi, M.L. de: Environmental temperature, X-irradiation and ageing in insects. Expl Gerontol. 10: 333-340 (1975). Ross, M.H. and Bras, G.: Food preference and length of life. Science 190: 165-167 (1975).
