Urological Survey Infection and Inflammation of the Genitourinary Tract Re: Atypical Microorganisms in Expressed Prostatic Secretion from Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Microbiological Results from a Case-Control Study J. Xiao, L. Ren, H. Lv, Q. Ding, S. Lou, W. Zhang and Z. Dong Department of Urology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, People’s Republic of China Urol Int 2013; 91: 410e416.
Abstract for this article http://dx.doi.org/10.1016/j.juro.2014.12.050 available at http://jurology.com/ Editorial Comment: These authors looked for atypical bacterial and viral infections in men presenting with type III prostatitis. They show increased bacteria and viral counts in men with more severe symptoms. Unfortunately there are no data in the study on the distribution of these bacteria in asymptomatic men. This is a key question, as Nickel et al demonstrated bacteria in approximately 8% of men with chronic prostatitis/chronic pelvic pain syndrome and normal controls.1 Edward M. Schaeffer, MD, PhD 1. Nickel JC, Alexander RB, Schaeffer AJ et al: Leukocytes and bacteria in men with chronic prostatitis/chronic pelvic pain syndrome compared to asymptomatic controls. J Urol 2003; 170: 818.
Re: Enterococcus faecalis Subverts and Invades the Host Urothelium in Patients with Chronic Urinary Tract Infection H. Horsley, J. Malone-Lee, D. Holland, M. Tuz, A. Hibbert, M. Kelsey, A. Kupelian and J. L. Rohn Centre for Clinical Science and Technology, Research Department of Clinical Physiology, Division of Medicine, University College London, Imaging Suite, Royal Veterinary College and Department of Microbiology, Whittington Hospital NHS Trust, London, United Kingdom PLoS One 2013; 8: e83637.
Abstract for this article http://dx.doi.org/10.1016/j.juro.2014.12.051 available at http://jurology.com/ Editorial Comment: Anderson et al first showed that uropathogenic bacteria form intracellular communities, where they can evade the host immune response.1 These authors investigate the role for bacterial pods/intracellular communities in individuals with lower urinary tract symptoms and low grade urinary tract infections. They show that these pods or communities exist and are most commonly populated by Enterococcus faecalis. How to move forward with these data will be the next big step. Edward M. Schaeffer, MD, PhD 1. Anderson GG, Palermo JJ, Schilling JD et al: Intracellular bacterial biofilm-like pods in urinary tract infections. Science 2003; 301: 105.
0022-5347/15/1933-0863/0 THE JOURNAL OF UROLOGY® © 2015 by AMERICAN UROLOGICAL ASSOCIATION EDUCATION
AND
RESEARCH, INC.
http://dx.doi.org/10.1016/j.juro.2014.12.050 Vol. 193, 863, March 2015 Printed in U.S.A.
www.jurology.com
j
863
Abstract for this article http://dx.doi.org/10.1016/j.juro.2014.12.050 available at http://jurology.com/ Editorial Comment: These authors looked for atypical bacterial and viral infections in men presenting with type III prostatitis. They show increased bacteria and viral counts in men with more severe symptoms. Unfortunately there are no data in the study on the distribution of these bacteria in asymptomatic men. This is a key question, as Nickel et al demonstrated bacteria in approximately 8% of men with chronic prostatitis/chronic pelvic pain syndrome and normal controls.1 Edward M. Schaeffer, MD, PhD 1. Nickel JC, Alexander RB, Schaeffer AJ et al: Leukocytes and bacteria in men with chronic prostatitis/chronic pelvic pain syndrome compared to asymptomatic controls. J Urol 2003; 170: 818.
Re: Enterococcus faecalis Subverts and Invades the Host Urothelium in Patients with Chronic Urinary Tract Infection H. Horsley, J. Malone-Lee, D. Holland, M. Tuz, A. Hibbert, M. Kelsey, A. Kupelian and J. L. Rohn Centre for Clinical Science and Technology, Research Department of Clinical Physiology, Division of Medicine, University College London, Imaging Suite, Royal Veterinary College and Department of Microbiology, Whittington Hospital NHS Trust, London, United Kingdom PLoS One 2013; 8: e83637.
Abstract for this article http://dx.doi.org/10.1016/j.juro.2014.12.051 available at http://jurology.com/ Editorial Comment: Anderson et al first showed that uropathogenic bacteria form intracellular communities, where they can evade the host immune response.1 These authors investigate the role for bacterial pods/intracellular communities in individuals with lower urinary tract symptoms and low grade urinary tract infections. They show that these pods or communities exist and are most commonly populated by Enterococcus faecalis. How to move forward with these data will be the next big step. Edward M. Schaeffer, MD, PhD 1. Anderson GG, Palermo JJ, Schilling JD et al: Intracellular bacterial biofilm-like pods in urinary tract infections. Science 2003; 301: 105.
0022-5347/15/1933-0863/0 THE JOURNAL OF UROLOGY® © 2015 by AMERICAN UROLOGICAL ASSOCIATION EDUCATION
AND
RESEARCH, INC.
http://dx.doi.org/10.1016/j.juro.2014.12.050 Vol. 193, 863, March 2015 Printed in U.S.A.
www.jurology.com
j
863
