Rapid mandible margins for intraoperative assessment Allison Mayer M.D., Mark C. Royer M.D., Don-Jon Summerlin DMD, MS, Michael Moore M.D., Chad Galer M.D., Taha Z. Shipchandler M.D., Mimi S. Kokoska M.D., FACS, MHCM, CPE PII: DOI: Reference:
S0196-0709(14)00106-9 doi: 10.1016/j.amjoto.2014.04.012 YAJOT 1387
To appear in:
American Journal of Otolaryngology–Head and Neck Medicine and Surgery
Received date: Accepted date:
30 January 2014 27 April 2014
Please cite this article as: Mayer Allison, Royer Mark C., Summerlin Don-Jon, Moore Michael, Galer Chad, Shipchandler Taha Z., Kokoska Mimi S., Rapid mandible margins for intraoperative assessment, American Journal of Otolaryngology–Head and Neck Medicine and Surgery (2014), doi: 10.1016/j.amjoto.2014.04.012
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ACCEPTED MANUSCRIPT Title Page Title: Rapid Mandible Margins for Intraoperative Assessment
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Allison Mayer, M.D. (Corresponding Author) 699 Riley Hospital Drive RI 0860 Department of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis, IN 46202
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Authors:
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Mark C. Royer, M.D. Department of Otolaryngology-Head and Neck Surgery Witham Memorial Hospital Lebanon, IN
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Don-Jon Summerlin, DMD, MS Adjunct Professor Department of Pathology and Laboratory Medicine Indiana University School of Medicine
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Michael Moore, M.D. Director, Division of Head and Neck Surgery Department of Otolaryngology-Head & Neck Surgery Indiana University School of Medicine Indianapolis, IN Chad Galer, M.D. Chief of Otolaryngology-Head and Neck Surgery Richard L. Roudebush V.A. Medical Center Indianapolis, IN Taha Z. Shipchandler, M.D, Department of Otolaryngology-Head and Neck Surgery Indiana University School of Medicine Indianapolis, IN Mimi S. Kokoska, M.D., FACS, MHCM, CPE Professor and Vice-Chair Department of Otolaryngology-Head & Neck Surgery Indiana University School of Medicine Indiana University Health Physicians
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ACCEPTED MANUSCRIPT Indianapolis, IN
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The partial results of this study were previously presented in poster format at the Annual Meeting of the American Academy of Otolaryngology-Head and Neck Surgery, Boston, MA, September 2010.
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Key Words: mandible; margins; core biopsy; bone dust; pathology; head and neck
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Abstract
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Objectives: To determine the feasibility of a rapid method of processing mandible bone
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margins for intraoperative histopathologic examination and to assess the relative value of fine, coarse, and core specimens in assessing bone margins.
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Study Design: Prospective histologic controlled study
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Setting: A tertiary level academic medical center histopathology laboratory. Subjects and Methods: Multiple bone samples were collected from fresh (