Research Original Investigation

Trabeculectomy for Open-Angle Glaucoma

19. AGIS (Advanced Glaucoma Intervention Study) Investigators. The Advanced Glaucoma Intervention Study, 8: risk of cataract formation after trabeculectomy. Arch Ophthalmol. 2001;119(12):1771-1779. 20. Musch DC, Gillespie BW, Niziol LM, et al; Collaborative Initial Glaucoma Treatment Study Group. Cataract extraction in the Collaborative Initial Glaucoma Treatment Study: incidence, risk factors, and the effect of cataract progression and extraction on clinical and quality-of-life outcomes. Arch Ophthalmol. 2006;124(12):1694-1700.

21. Awai-Kasaoka N, Inoue T, Takihara Y, et al. Impact of phacoemulsification on failure of trabeculectomy with mitomycin-C. J Cataract Refract Surg. 2012;38(3):419-424. 22. Rebolleda G, Muñoz-Negrete FJ. Phacoemulsification in eyes with functioning filtering blebs: a prospective study. Ophthalmology. 2002;109(12):2248-2255. 23. AGIS Investigators. The Advanced Glaucoma Intervention Study (AGIS), 11: risk factors for failure of trabeculectomy and argon laser trabeculoplasty. Am J Ophthalmol. 2002;134(4):481-498.

24. Fontana H, Nouri-Mahdavi K, Caprioli J. Trabeculectomy with mitomycin C in pseudophakic patients with open-angle glaucoma: outcomes and risk factors for failure. Am J Ophthalmol. 2006;141(4):652-659. 25. Shingleton BJ, Alfano C, O’Donoghue MW, Rivera J. Efficacy of glaucoma filtration surgery in pseudophakic patients with or without conjunctival scarring. J Cataract Refract Surg. 2004;30(12):2504-2509.

OPHTHALMIC IMAGES

Racial Melanosis: A Striking Presentation Amir A. Azari, MD; Julia Agapov, DO, MD; Mozhgan Rezaei Kanavi, MD; Christina Larsen, MD; Heather D. Potter, MD; Daniel M. Albert, MD A

B

C

Darkly pigmented conjunctival areas are seen in the right (A) and left (B) eyes of an 87-year-old African American woman with a history of glaucoma and bilateral trabeculectomy. The dark conjunctival lesions have been present for at least 40 years and were seen before any glaucoma medications had been started. There is no history of epinephrine use. C, Histopathological analysis reveals increased pigmentation of epithelial cells, predominantly in the basal layer (hematoxylin-eosin, original magnification ×100).

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Racial melanosis: a striking presentation.

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