Accepted Manuscript Quality of Life in Patients With Advanced Cancer at the End of Life as Measured by the McGill Quality of Life Questionnaire: A Survey in China Jing Cui, PhD Fang Fang, MD Fengping Shen, MS Lijuan Song, MS Lingjun Zhou, PhD Xiuqiang Ma, MD Jijun Zhao, BSc PII:
S0885-3924(14)00229-2
DOI:
10.1016/j.jpainsymman.2014.02.016
Reference:
JPS 8662
To appear in:
Journal of Pain and Symptom Management
Received Date: 24 September 2013 Revised Date:
27 January 2014
Accepted Date: 18 February 2014
Please cite this article as: Cui J, Fang F, Shen F, Song L, Zhou L, Ma X, Zhao J, Quality of Life in Patients With Advanced Cancer at the End of Life as Measured by the McGill Quality of Life Questionnaire: A Survey in China, Journal of Pain and Symptom Management (2014), doi: 10.1016/ j.jpainsymman.2014.02.016. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Original Article
13-00532R1
Quality of Life in Patients With Advanced Cancer at the End of Life as Measured by the
RI PT
McGill Quality of Life Questionnaire: A Survey in China
Jing Cui, PhD, Fang Fang, MD, Fengping Shen, MS, Lijuan Song, MS, Lingjun Zhou, PhD,
M AN U
SC
Xiuqiang Ma, MD, and Jijun Zhao, BSc
School of Nursing (J.C.), Institute for Translational Medicine (L.Z.), and Department of Health Statistics (X.M.), Second Military Medical University, Shanghai; Departments of Interventional Radiology (F.F.), Oncology (F.S.), and Nursing (J.Z.), Changhai Hospital, Second Military
TE D
Medical University, Shanghai; and Department of Nursing (L.S.), Shanghai Academy of Health Science, Shanghai, People’s Republic of China
EP
Drs. Cui and Fang contributed equally to this article.
AC C
Address correspondence to: Jijun Zhao, BSc
No. 168 Changhai Road Shanghai, PRC 200433
E-mail: [email protected]
1
ACCEPTED MANUSCRIPT
Abstract Context. Quality of life (QOL) is the main outcome measure for patients with advanced
RI PT
cancer at the end of life (EOL). The McGill Quality of Life questionnaire (MQOL) is designed specifically for palliative care patients, and has been translated and validated in Hong Kong and Taiwan.
SC
Objectives. This study aimed to investigate the QOL of patients with advanced cancer using
M AN U
the MQOL-Taiwan version after cultural adaptation to the Chinese mainland. Methods. A cross-sectional survey design was used. QOL data from patients with advanced cancer were gathered from 13 hospitals including five tertiary hospitals, six secondary hospitals, and community health care service centers in Shanghai and analyzed. QOL was assessed using
TE D
the MQOL-Chinese version. Statistical analyses were performed using descriptive statistics, multiple regression analysis, and Spearman rank correlation analysis. Results. A total of 531 cancer patients (297 male, 234 female) in 13 hospitals were
EP
recruited into the study and administered the MQOL-Chinese. The score of the support subscale
AC C
was highest (6.82), and the score of the existential well-being subscale was the lowest (4.65). The five physical symptoms most frequently listed on the MQOL-Chinese were pain, loss of appetite, fatigue, powerless, and dyspnea. Participants’ sex, educational level, number of children, and disclosure of the disease, and hospital size were associated with their overall QOL. The Spearman rank correlation analysis found that Karnofsky Performance Status scores correlated with the MQOL-Chinese single item score, physical well-being, psychological well-being, existential well-being, and support domains (P
S0885-3924(14)00229-2
DOI:
10.1016/j.jpainsymman.2014.02.016
Reference:
JPS 8662
To appear in:
Journal of Pain and Symptom Management
Received Date: 24 September 2013 Revised Date:
27 January 2014
Accepted Date: 18 February 2014
Please cite this article as: Cui J, Fang F, Shen F, Song L, Zhou L, Ma X, Zhao J, Quality of Life in Patients With Advanced Cancer at the End of Life as Measured by the McGill Quality of Life Questionnaire: A Survey in China, Journal of Pain and Symptom Management (2014), doi: 10.1016/ j.jpainsymman.2014.02.016. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Original Article
13-00532R1
Quality of Life in Patients With Advanced Cancer at the End of Life as Measured by the
RI PT
McGill Quality of Life Questionnaire: A Survey in China
Jing Cui, PhD, Fang Fang, MD, Fengping Shen, MS, Lijuan Song, MS, Lingjun Zhou, PhD,
M AN U
SC
Xiuqiang Ma, MD, and Jijun Zhao, BSc
School of Nursing (J.C.), Institute for Translational Medicine (L.Z.), and Department of Health Statistics (X.M.), Second Military Medical University, Shanghai; Departments of Interventional Radiology (F.F.), Oncology (F.S.), and Nursing (J.Z.), Changhai Hospital, Second Military
TE D
Medical University, Shanghai; and Department of Nursing (L.S.), Shanghai Academy of Health Science, Shanghai, People’s Republic of China
EP
Drs. Cui and Fang contributed equally to this article.
AC C
Address correspondence to: Jijun Zhao, BSc
No. 168 Changhai Road Shanghai, PRC 200433
E-mail: [email protected]
1
ACCEPTED MANUSCRIPT
Abstract Context. Quality of life (QOL) is the main outcome measure for patients with advanced
RI PT
cancer at the end of life (EOL). The McGill Quality of Life questionnaire (MQOL) is designed specifically for palliative care patients, and has been translated and validated in Hong Kong and Taiwan.
SC
Objectives. This study aimed to investigate the QOL of patients with advanced cancer using
M AN U
the MQOL-Taiwan version after cultural adaptation to the Chinese mainland. Methods. A cross-sectional survey design was used. QOL data from patients with advanced cancer were gathered from 13 hospitals including five tertiary hospitals, six secondary hospitals, and community health care service centers in Shanghai and analyzed. QOL was assessed using
TE D
the MQOL-Chinese version. Statistical analyses were performed using descriptive statistics, multiple regression analysis, and Spearman rank correlation analysis. Results. A total of 531 cancer patients (297 male, 234 female) in 13 hospitals were
EP
recruited into the study and administered the MQOL-Chinese. The score of the support subscale
AC C
was highest (6.82), and the score of the existential well-being subscale was the lowest (4.65). The five physical symptoms most frequently listed on the MQOL-Chinese were pain, loss of appetite, fatigue, powerless, and dyspnea. Participants’ sex, educational level, number of children, and disclosure of the disease, and hospital size were associated with their overall QOL. The Spearman rank correlation analysis found that Karnofsky Performance Status scores correlated with the MQOL-Chinese single item score, physical well-being, psychological well-being, existential well-being, and support domains (P
