Risk Management and Healthcare Policy
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Quality measure attainment with dapagliflozin plus metformin extended-release as initial combination therapy in patients with type 2 diabetes: a post hoc pooled analysis of two clinical studies This article was published in the following Dove Press journal: Risk Management and Healthcare Policy 14 October 2016 Number of times this article has been viewed
Kelly F Bell Arie Katz John J Sheehan AstraZeneca, Wilmington, DE, USA
Correspondence: Kelly Bell Health Economics and Outcomes Research, AstraZeneca, US Medical Affairs, 1800 Concord Pike, PO Box 15437, Wilmington, DE, 19850, USA Tel + 1 267-417-6220 Email
[email protected] Background: The use of quality measures attempts to improve safety and health outcomes and to reduce costs. In two Phase III trials in treatment-naive patients with type 2 diabetes, dapagliflozin 5 or 10 mg/d as initial combination therapy with metformin extended-release (XR) significantly reduced glycated hemoglobin (A1C) from baseline to 24 weeks and allowed higher proportions of patients to achieve A1C