EDITORIALS

Pulling it all together: William

B. Kannel,

MD, and Philip

Changing A. Wolf,

MD. Boston,

From the BU-Framingham Study, Boston University School of Medicine. Received for publication May 14, 1991; accepted July 1, 1991. Reprint requests: William B. Kannel, MD, BU-Framingham Study, 5 Thurber St., Boston, MA 01701. 411133672

I. Coronary heart disease risk factor prediction

Table 1. Find

points

the cardiovascular Muss.

Prevention of cardiovascular disease can be approached from the standpoint of public health measures to alter the ecology to one more favorable to cardiovascular health, health education to enable the

chart

for each risk factor Age (If female)

Age 30 31 32 33 34 35 36 37 38 39 40 41 42-43

Age

-12 -11 -9 -8 -6 -5 -4 -3 -2 -1

44 45-46 47-48 49-50 51-52 53-55 56-60 61-67 68-74

Pts

Pts

Age

Pts

3 4 5 6 7 8 9 10 11

30 31 32-33 34 35-36 37-38 39 40-41 42-43 44-45 46-47 48-49 50-51

-2 -1

52-54 55-56 57-59 60-61 62-64 65-67 68-70 71-73 74

11 12 13 14 15 16 17 18 19

7 6 5 4 3 2 1 0 -1 -2 -3 -4 -5 -6 -7

points

for all risk

Systolic

0 1 2 3 4 5 6 7 8 9 10

blood pressure

Total-C

Pts

SBP

Pts

139-151 152-166 167-182 183-199 200-219 220-239 240-262 263-288 289-315 316-330

-3 -2 -1

98-104 105-112 113-120 121-129 130-139 140-149 150-160 161-172 173-185

-2 -1

0 1 2 3 4 5 6

Pts

Other Cigarettes Diabetic-male Diabetic-female ECG-LVH

0 1 2 3 4 5 6

4 3 6 9

0 pts for each NO

factors

-I+ HDL-C Total C Age NOTE: Minus points subtract from total. Reproduced 264

Age

Total-Cholesterol

25-26 27-29 30-32 33-35 36-38 39-42 43-46 47-50 51-55 56-60 61-66 67-73 74-80 81-87 88-96

Pts, Patients;

Pts

0 1 2

HDL-Cholesterol

2. Sum

Age (If male)

PtS

HDL-C

outlook

+

HDL, high-density lipoprotein; C, cholesterol; with permission. “Risk Factor Prediction Kit,”

+ SBP

+ Smoker

+ Diabetes

SBP, systolic blood pressure; ECG, electrocardiogram; 1990. Copyright, American Heart Association,

ECG-LVH=

LVH,

left ventricular

Point

total

hypertrophy

Volume Number

123 1

Risk assessment profiles for coronary disease

public to make necessary changes on their own behalf, and preventive medicine for persons who are at high risk. The high prevalence of cardiovascular risk factors in the general population and the high incidence and lethal nature of cardiovascular disease require the population approach if major inroads are to be made. Preventive medicine is best directed at high-risk candidates who require individualized and professional management. For the latter, multivariate risk assessment is necessary to select candidates for cardiovascular disease and to judge the possible efficacy of treatment. Risk factors tend to cluster, making single risk factor intervention inefficient.

3. Look

up risk

corresponding

to point

total

Pts

5 yr

10 yr

Pts

5 Yr

sl

Pulling it all together: changing the cardiovascular outlook.

EDITORIALS Pulling it all together: William B. Kannel, MD, and Philip Changing A. Wolf, MD. Boston, From the BU-Framingham Study, Boston Univers...
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