The Journal of Craniofacial Surgery • Volume 25, Number 6, November 2014
Brief Clinical Studies
10. Block BB, Kuo E, Zalzal HG, et al. In vitro effects of acid and pepsin on middle ear epithelial cell viability and MUC5B gene expression. Arch Otolaryngol Head Neck Surg 2010;136:37–42 11. Klokkenburg JJC, Hoeve HLJ, Francke J, et al. Bile acids identified in middle ear effusions of children with otitis media with effusion. Laryngoscope 2009;119:396–400 12. Sade J. Pathology and pathogenesis of serous otitis media. Arch Otolaryngol. 1966;84:297–305 13. Park SN, Yeo SW. Effects of antibiotics and steroid on middle ear mucosa in rats with experimental acute otitis media. Acta Otolaryngol 2001;121:808–812 14. Samuels TL, Johnston N. Pepsin as a causal agent of inflammation during nonacidic reflux. Otolaryngol Head Neck Surg 2009;141:559–563 15. Crapko M, Kerschner JE, Syring M, et al. Role of extra-esophageal reflux in chronic otitis media with effusion. Laryngoscope 2007;117:1419–1423 16. Nyc MA, Kim SG, Kapoor A, et al. Measuring thickness of middle ear mucosa using MRI and CT imaging versus histopathology. Int J Otolarygol 2012;2012:962496 17. Palva T, Northrop C, Ramsay H. Foreign body neonatal otitis media in infants. Otol Neurotol 2001;22:433–443 18. Chonmaitree T, Patel J, Lett-Brown M, et al. Virus and bacteria enhance histamine production in middle ear fluids of children with acute otitis media. J Infect Dis 1994;169:1265–1270 19. Short KR, Diavatopoulos DA, Thornton R, et al. Influenza virus induces bacterial and nonbacterial otitis media. J Infect Dis 2011;204:1857–1865 20. Tos M. Pathology and pathogenesis of chronic secretory otitis media in childhood. HNO 1976;24:37–47 21. Lin J, Thomasen PC, Tono T, et al. Mucin production and mucous cell metaplasia in otitis media. Int J Otolaryngol 2012;2012:745325 22. Friedmann I. The pathology of otitis media. J Clin Pathol 1956;9:229–236 23. Kauer WK, Peters JH, DeMeester TR, et al. Composition and concentration of bile acid reflux into the esophagus of patients with gastroesophageal reflux disease. Surg 1997;122:874–881 24. Develioglu ON, Yılmaz M, Caglar E, et al. Ototoxic effect of gastric reflux: an experimental model. J Craniofac Surg 2013;24:640–644 25. Gelderblom WC, Smuts CM, Abel S, et al. Effect of fumonisin B1 on the levels and fatty acid composition of selected lipids in rat liver in vivo. Food Chem Toxicol 1997;35:647–656 26. Zen Junior JHZ, Negro AD, Neto JAC, et al. Experimental model of smoking and simulation of reflux with acid and pepsin in rats. Acta Cir Bras 2012;27:18–22
Psychologic Health Status of Patients Undergoing Orthognathic Surgery Sheng Yao, DDS, MSc,*†‡ Jie Zhou, DDS, MSc,‡ Zubing Li, DDS, PhD*†
From the *Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, †Key Laboratory of Oral Biomedical Engineering (Wuhan University), Ministry of Education; ‡Department of Stomatology, First Hospital of Wuhan, Wuhan, China. Received November 13, 2013. Accepted for publication April 20, 2014. Address correspondence and reprint requests to Zubing Li, DDS, PhD, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Key Laboratory of Oral Biomedical Engineering, Wuhan University, Ministry of Education, 237 Luoyu Rd, Wuhan, China; E-mail: [email protected] The authors report no conflicts of interest. Copyright © 2014 by Mutaz B. Habal, MD ISSN: 1049-2275 DOI: 10.1097/SCS.0000000000001042
e540
Background: The appearance and dysfunction of deformities may cause psychologic disorders in patients. The aim of this study was to assess the psychologic health status of patients undergoing orthognathic surgery and its relationship with demographic characteristics, social activityof the individuals, and severity of maxillofacial deformity. Methods: As a tool for assessing the psychologic health status, the Symptom Checklist-90 (SCL-90) questionnaire was used on 318 patients undergoing orthognathic surgery at the Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, China from January 2006 to November 2012. t-Test was used to compare the psychologic health status between the 318 patients and 200 healthy volunteers. Variance analysis (analysis of variance) was applied for assessing the relationship between the psychologic health status and the variables of the study. Results: The SCL-90 total score of the patients undergoing orthognathic surgery was higher than that of the healthy volunteers (P < 0.05). Results of the t-test revealed statistically significant difference (P < 0.05) in the symptom dimensions of obsessive-compulsive, interpersonal sensitivity, depression, and paranoid ideation. An association between sex and the SCL-90 total score was observed (F = 11.293; P = 0.001 and P
Brief Clinical Studies
10. Block BB, Kuo E, Zalzal HG, et al. In vitro effects of acid and pepsin on middle ear epithelial cell viability and MUC5B gene expression. Arch Otolaryngol Head Neck Surg 2010;136:37–42 11. Klokkenburg JJC, Hoeve HLJ, Francke J, et al. Bile acids identified in middle ear effusions of children with otitis media with effusion. Laryngoscope 2009;119:396–400 12. Sade J. Pathology and pathogenesis of serous otitis media. Arch Otolaryngol. 1966;84:297–305 13. Park SN, Yeo SW. Effects of antibiotics and steroid on middle ear mucosa in rats with experimental acute otitis media. Acta Otolaryngol 2001;121:808–812 14. Samuels TL, Johnston N. Pepsin as a causal agent of inflammation during nonacidic reflux. Otolaryngol Head Neck Surg 2009;141:559–563 15. Crapko M, Kerschner JE, Syring M, et al. Role of extra-esophageal reflux in chronic otitis media with effusion. Laryngoscope 2007;117:1419–1423 16. Nyc MA, Kim SG, Kapoor A, et al. Measuring thickness of middle ear mucosa using MRI and CT imaging versus histopathology. Int J Otolarygol 2012;2012:962496 17. Palva T, Northrop C, Ramsay H. Foreign body neonatal otitis media in infants. Otol Neurotol 2001;22:433–443 18. Chonmaitree T, Patel J, Lett-Brown M, et al. Virus and bacteria enhance histamine production in middle ear fluids of children with acute otitis media. J Infect Dis 1994;169:1265–1270 19. Short KR, Diavatopoulos DA, Thornton R, et al. Influenza virus induces bacterial and nonbacterial otitis media. J Infect Dis 2011;204:1857–1865 20. Tos M. Pathology and pathogenesis of chronic secretory otitis media in childhood. HNO 1976;24:37–47 21. Lin J, Thomasen PC, Tono T, et al. Mucin production and mucous cell metaplasia in otitis media. Int J Otolaryngol 2012;2012:745325 22. Friedmann I. The pathology of otitis media. J Clin Pathol 1956;9:229–236 23. Kauer WK, Peters JH, DeMeester TR, et al. Composition and concentration of bile acid reflux into the esophagus of patients with gastroesophageal reflux disease. Surg 1997;122:874–881 24. Develioglu ON, Yılmaz M, Caglar E, et al. Ototoxic effect of gastric reflux: an experimental model. J Craniofac Surg 2013;24:640–644 25. Gelderblom WC, Smuts CM, Abel S, et al. Effect of fumonisin B1 on the levels and fatty acid composition of selected lipids in rat liver in vivo. Food Chem Toxicol 1997;35:647–656 26. Zen Junior JHZ, Negro AD, Neto JAC, et al. Experimental model of smoking and simulation of reflux with acid and pepsin in rats. Acta Cir Bras 2012;27:18–22
Psychologic Health Status of Patients Undergoing Orthognathic Surgery Sheng Yao, DDS, MSc,*†‡ Jie Zhou, DDS, MSc,‡ Zubing Li, DDS, PhD*†
From the *Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, †Key Laboratory of Oral Biomedical Engineering (Wuhan University), Ministry of Education; ‡Department of Stomatology, First Hospital of Wuhan, Wuhan, China. Received November 13, 2013. Accepted for publication April 20, 2014. Address correspondence and reprint requests to Zubing Li, DDS, PhD, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Key Laboratory of Oral Biomedical Engineering, Wuhan University, Ministry of Education, 237 Luoyu Rd, Wuhan, China; E-mail: [email protected] The authors report no conflicts of interest. Copyright © 2014 by Mutaz B. Habal, MD ISSN: 1049-2275 DOI: 10.1097/SCS.0000000000001042
e540
Background: The appearance and dysfunction of deformities may cause psychologic disorders in patients. The aim of this study was to assess the psychologic health status of patients undergoing orthognathic surgery and its relationship with demographic characteristics, social activityof the individuals, and severity of maxillofacial deformity. Methods: As a tool for assessing the psychologic health status, the Symptom Checklist-90 (SCL-90) questionnaire was used on 318 patients undergoing orthognathic surgery at the Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, China from January 2006 to November 2012. t-Test was used to compare the psychologic health status between the 318 patients and 200 healthy volunteers. Variance analysis (analysis of variance) was applied for assessing the relationship between the psychologic health status and the variables of the study. Results: The SCL-90 total score of the patients undergoing orthognathic surgery was higher than that of the healthy volunteers (P < 0.05). Results of the t-test revealed statistically significant difference (P < 0.05) in the symptom dimensions of obsessive-compulsive, interpersonal sensitivity, depression, and paranoid ideation. An association between sex and the SCL-90 total score was observed (F = 11.293; P = 0.001 and P
