IJMS Vol 41, No 3, Supplement May 2016
Poster
Proteomics Approaches Shed New Light on Traditional Iranian Medicine Mina Movahhed1, Zohreh Poursaleh2*
Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2 Students’ Research Office, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran 1
52
Abstract
Background: Until now, Iranian traditional medicine (ITM) had been extensively based on Iranian philosophy in theoretical approach in diagnosis and treatment, with doubts on academic medicine. Nevertheless, the diagnosis of temperaments, herbal standardization, and quality control had been with the obscurity of functional molecules and their action mechanisms. Proteomics is a potent board to the mechanistic investigation of ITM and has been comprehensively applied profile drug-regulated proteins. In this review, we assessed the application of this modern molecular biological method in the identification of temperaments and drug targets of ITM. Methods: All available studies related to proteomics in traditional medicine, alternative and complementary medicine, including books, journals, and other references were studied and assessed. Results: The present review showed the phenotypes of the various temperaments in healthy individuals, that is to say, same proteins with different dynamic properties. Therefore, the usefulness of proteomics seems authoritative to understand the means by which the molecular pathways protected in ITM. This might be also the key clinical viewpoint on this new approach for enabling the integration of Iranian traditional medicine and modern biological science and technology, as well for upholding the internationalization of ITM. Conclusion: Proteomics, as a powerful tool for systems biology, is an essential research methodology for understanding the mechanisms of traditional medicine. Further investigation on the applications of advanced proteomics in temperaments, herbal standardization, and quality control in ITM is recommended. Keywords ● Proteomics ● Medicine ● Traditional ● Temperament ● Complementary therapies
Iran J Med Sci Supplement May 2016; Vol 41 No 3
Poster
Proteomics Approaches Shed New Light on Traditional Iranian Medicine Mina Movahhed1, Zohreh Poursaleh2*
Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2 Students’ Research Office, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran 1
52
Abstract
Background: Until now, Iranian traditional medicine (ITM) had been extensively based on Iranian philosophy in theoretical approach in diagnosis and treatment, with doubts on academic medicine. Nevertheless, the diagnosis of temperaments, herbal standardization, and quality control had been with the obscurity of functional molecules and their action mechanisms. Proteomics is a potent board to the mechanistic investigation of ITM and has been comprehensively applied profile drug-regulated proteins. In this review, we assessed the application of this modern molecular biological method in the identification of temperaments and drug targets of ITM. Methods: All available studies related to proteomics in traditional medicine, alternative and complementary medicine, including books, journals, and other references were studied and assessed. Results: The present review showed the phenotypes of the various temperaments in healthy individuals, that is to say, same proteins with different dynamic properties. Therefore, the usefulness of proteomics seems authoritative to understand the means by which the molecular pathways protected in ITM. This might be also the key clinical viewpoint on this new approach for enabling the integration of Iranian traditional medicine and modern biological science and technology, as well for upholding the internationalization of ITM. Conclusion: Proteomics, as a powerful tool for systems biology, is an essential research methodology for understanding the mechanisms of traditional medicine. Further investigation on the applications of advanced proteomics in temperaments, herbal standardization, and quality control in ITM is recommended. Keywords ● Proteomics ● Medicine ● Traditional ● Temperament ● Complementary therapies
Iran J Med Sci Supplement May 2016; Vol 41 No 3
