Transfusion Medicine, 1992.2, 135-142
Proteolytic activity during storage of platelets in plasma J. Wallvik,*f A. M. Suontaka*t and M. Blomback* *Department ofCIinical Chemisiry and Blood Coagularion, Deparrment of Clinical Immunology and ?Blood Transfusion Service. Karolinska Hospital, Stockholm, Sweden Received 5 February 1991; acceptedfor publication I7 September 1991
demonstrated while no TAT and D-dimers could be detected. The cause of the formation of FPA was studied in experiment 2; three bags of PC and four of PPP were prepared from each of 16 donors. To the PC and three of the PPP bags either hirudin, aprotinin or no enzyme inhibitor (control) was added. To the fourth PPP bag extra CPD was added to evaluate the effect of pH. Hirudin decreased the formation of FPA (P
Proteolytic activity during storage of platelets in plasma J. Wallvik,*f A. M. Suontaka*t and M. Blomback* *Department ofCIinical Chemisiry and Blood Coagularion, Deparrment of Clinical Immunology and ?Blood Transfusion Service. Karolinska Hospital, Stockholm, Sweden Received 5 February 1991; acceptedfor publication I7 September 1991
demonstrated while no TAT and D-dimers could be detected. The cause of the formation of FPA was studied in experiment 2; three bags of PC and four of PPP were prepared from each of 16 donors. To the PC and three of the PPP bags either hirudin, aprotinin or no enzyme inhibitor (control) was added. To the fourth PPP bag extra CPD was added to evaluate the effect of pH. Hirudin decreased the formation of FPA (P
