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Can imaging accurately diagnose lymph node involvement? Jelle O. Barentsz and Harriet C. Thoeny Refers to Van den Bergh, L. et al. Final analysis of a prospective trial on functional imaging for nodal staging in patients with prostate cancer at high risk for lymph node involvement. Urol. Oncol. http://dx.doi.org/10.1016/j.urolonc.2014.11.008 (2015)

Most metastatic lymph nodes in patients with prostate cancer go undetected by current imaging techniques and limited pelvic lymph node dissection (PLND), as they are small and located in difficult-to-reach areas. As the only current alternative is an extended PLND, the search for more accurate imaging techniques continues. In patients with prostate cancer who are at risk of lymph node metastases, conventional cross-sectional imaging techniques such as CT and MRI do not detect 70% of metastatic lymph nodes, as the majority are small (

Prostate cancer: Can imaging accurately diagnose lymph node involvement?

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