e u r o p e a n j o u r n a l o f p a e d i a t r i c n e u r o l o g y x x x ( 2 0 1 5 ) 1 e5
Official Journal of the European Paediatric Neurology Society
Original article
Prospective analysis on brain magnetic resonance imaging in children Ariane Biebl a,*, Bettina Frechinger b, Christine Maria Fellner c, Margit Ehrenmu¨ller d, Brigitte Povysil b, Franz Fellner c, Klaus Schmitt a, Dieter Furthner a a
Children's Hospital, Department of Paediatrics, Krankenhausstr. 26-30, 4020 Linz, Austria Children's Hospital, Department of Paediatric Radiology, Krankenhausstr. 26-30, 4020 Linz, Austria c General Hospital, Department of Radiology, Krankenhausstr. 9, 4020 Linz, Austria d University of Applied Sciences, Statistics, Wehrgrabengasse 1, 4400 Steyr, Austria b
article info
abstract
Article history:
Background: Previous studies have addressed the prevalence of incidental findings in adult
Received 2 November 2014
populations. There are few studies following paediatric patients, most of data were
Received in revised form
retrieved retrospectively. We conducted a prospective study to determine the prevalence of
17 January 2015
incidental, pathologic and normal findings in a symptomatic paediatric population.
Accepted 19 January 2015
Methods: The subjects of this prospective single centre study are 436 children aged 0e18 years with clinical symptoms and subsequent first brain MRI. Normal, incidental as well as
Keywords:
pathologic MRI findings are documented in association with age, gender, neurological
Brain
examination and previous investigations (CCT, EEG). Secondary outcome parameters are
Incidental findings
defined as MRI results and their implications. Two board-certified radiologists prospec-
Magnetic resonance imaging (MRI)
tively analysed MR images without knowing the result from each other.
Prospective
Results: The 436 patients with brain MRI were categorized into three groups as follows: 155
Symptomatic children
(35.5%) patients had normal findings, 163 (37.4%) had incidental findings and 118 (27.1%) had pathological findings in brain MRI. When adding patients with pathologic and incidental findings we report even more (47.9%). We analysed the correlation between neurologic examination and MRI result and it was significant (p-value 0.0008). The p-value for concordance of both radiology reports was
Official Journal of the European Paediatric Neurology Society
Original article
Prospective analysis on brain magnetic resonance imaging in children Ariane Biebl a,*, Bettina Frechinger b, Christine Maria Fellner c, Margit Ehrenmu¨ller d, Brigitte Povysil b, Franz Fellner c, Klaus Schmitt a, Dieter Furthner a a
Children's Hospital, Department of Paediatrics, Krankenhausstr. 26-30, 4020 Linz, Austria Children's Hospital, Department of Paediatric Radiology, Krankenhausstr. 26-30, 4020 Linz, Austria c General Hospital, Department of Radiology, Krankenhausstr. 9, 4020 Linz, Austria d University of Applied Sciences, Statistics, Wehrgrabengasse 1, 4400 Steyr, Austria b
article info
abstract
Article history:
Background: Previous studies have addressed the prevalence of incidental findings in adult
Received 2 November 2014
populations. There are few studies following paediatric patients, most of data were
Received in revised form
retrieved retrospectively. We conducted a prospective study to determine the prevalence of
17 January 2015
incidental, pathologic and normal findings in a symptomatic paediatric population.
Accepted 19 January 2015
Methods: The subjects of this prospective single centre study are 436 children aged 0e18 years with clinical symptoms and subsequent first brain MRI. Normal, incidental as well as
Keywords:
pathologic MRI findings are documented in association with age, gender, neurological
Brain
examination and previous investigations (CCT, EEG). Secondary outcome parameters are
Incidental findings
defined as MRI results and their implications. Two board-certified radiologists prospec-
Magnetic resonance imaging (MRI)
tively analysed MR images without knowing the result from each other.
Prospective
Results: The 436 patients with brain MRI were categorized into three groups as follows: 155
Symptomatic children
(35.5%) patients had normal findings, 163 (37.4%) had incidental findings and 118 (27.1%) had pathological findings in brain MRI. When adding patients with pathologic and incidental findings we report even more (47.9%). We analysed the correlation between neurologic examination and MRI result and it was significant (p-value 0.0008). The p-value for concordance of both radiology reports was
