Prolonged indomethacin therapy for the prevention of recurrences of patent ductus arteriosus C a t h y H a m m e r m a n , MD.* and Mary .Jane A r a m b u r o , MD From the University of Chicago Medical Center. Chicago. Illinois

We tested the hypothesis that prolonged maintenance indomethacin therapy would allow more effective closure of patent ductus arteriosus (PDA) and thereby decrease the recurrence rate. Thirty-nine low birthweight neonates (