CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2017; 23: 1533-1539 DOI: 10.12659/MSM.900856
Prognostic Value of High-Sensitivity C-Reactive Protein, Procalcitonin and Pancreatic Stone Protein in Pediatric Sepsis
Received: 2016.08.01 Accepted: 2016.08.25 Published: 2017.03.30
Authors’ Contribution: Study Design A Data Collection B Analysis C Statistical Data Interpretation D Manuscript Preparation E Literature Search F Funds Collection G
A 1 B 2 C 1 DF 3 EG 1
Qiong Wu* Jun Nie* Fu-xia Wu Xiu-lan Zou Feng-yi Chen
1 Department of Pediatrics, People’s Hospital of China Three Gorges University, The 1st People’s Hospital of Yichang, Yichang, Hubei, P.R. China 2 Department of Cardiothoracic Surgery, People’s Hospital of China Three Gorges University, The 1st People’s Hospital of Yichang, Yichang, Hubei, P.R. China 3 Department of Endocrinology, People’s Hospital of China Three Gorges University, The 1st People’s Hospital of Yichang, Yichang, Hubei, P.R. China
Corresponding Author: Source of support:
* These two authors contributed equally to this work Qiong Wu, e-mail: [email protected] This study was supported by the National Natural Science Foundation of China (No.832305823) and the Science Research and Development Project of Yichang (No. 2013 A13301-18)
Background:
Material/Methods:
Results:
Conclusions:
To investigate the prognostic value of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), and pancreatic stone protein (PSP) in children with sepsis. A total of 214 patients with sepsis during hospitalization were enrolled. Serum levels of PCT, hs-CRP, and PSP were measured on day 1 of hospitalization and the survival rates of children were recorded after a follow-up of 28 days. Pearson’s correlation analysis was conducted to test the association of PCT, hs-CRP, and PSP with pediatric critical illness score (PCIS). Logistic regression models were used to analyze the risk factors contributing to patients’ death. The AUC was used to determine the value of PCT, hs-CRP, and PSP in the prognosis of patients with sepsis. The expression of PCT, hs-CRP, and PSP in the dying patients was higher than in the surviving patients (p
Prognostic Value of High-Sensitivity C-Reactive Protein, Procalcitonin and Pancreatic Stone Protein in Pediatric Sepsis
Received: 2016.08.01 Accepted: 2016.08.25 Published: 2017.03.30
Authors’ Contribution: Study Design A Data Collection B Analysis C Statistical Data Interpretation D Manuscript Preparation E Literature Search F Funds Collection G
A 1 B 2 C 1 DF 3 EG 1
Qiong Wu* Jun Nie* Fu-xia Wu Xiu-lan Zou Feng-yi Chen
1 Department of Pediatrics, People’s Hospital of China Three Gorges University, The 1st People’s Hospital of Yichang, Yichang, Hubei, P.R. China 2 Department of Cardiothoracic Surgery, People’s Hospital of China Three Gorges University, The 1st People’s Hospital of Yichang, Yichang, Hubei, P.R. China 3 Department of Endocrinology, People’s Hospital of China Three Gorges University, The 1st People’s Hospital of Yichang, Yichang, Hubei, P.R. China
Corresponding Author: Source of support:
* These two authors contributed equally to this work Qiong Wu, e-mail: [email protected] This study was supported by the National Natural Science Foundation of China (No.832305823) and the Science Research and Development Project of Yichang (No. 2013 A13301-18)
Background:
Material/Methods:
Results:
Conclusions:
To investigate the prognostic value of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), and pancreatic stone protein (PSP) in children with sepsis. A total of 214 patients with sepsis during hospitalization were enrolled. Serum levels of PCT, hs-CRP, and PSP were measured on day 1 of hospitalization and the survival rates of children were recorded after a follow-up of 28 days. Pearson’s correlation analysis was conducted to test the association of PCT, hs-CRP, and PSP with pediatric critical illness score (PCIS). Logistic regression models were used to analyze the risk factors contributing to patients’ death. The AUC was used to determine the value of PCT, hs-CRP, and PSP in the prognosis of patients with sepsis. The expression of PCT, hs-CRP, and PSP in the dying patients was higher than in the surviving patients (p
![[Prognostic value of lipopolysaccharide binding protein and procalcitonin in patients with severe sepsis and septic shock admitted to intensive care].](/assets/img/hold.png)
